Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6310355 | 0.86 | CYP1A2 (0.40) | NPSR1LMNAPOLBALDH1A1TDP1 | |
| SCHEMBL14940700 | 0.83 | ALDH1A1 (0.43) | NPSR1LMNAALDH1A1TDP1CYP2C9 | |
| SCHEMBL3279670 | 0.77 | HDAC3 (0.39) | LMNAALDH1A1TSHRHTTKDM4E | |
| SCHEMBL6667980 | 0.76 | CA2 (0.50) | NPSR1LMNAALDH1A1TDP1CYP2C9 | |
| Hydrochloric Acid SCHEMBL329123 | 0.75 | HDAC3 (0.38) | LMNAALDH1A1TSHRHTTKDM4E | |
| SCHEMBL17870956 | 0.75 | ALDH1A1 (0.42) | NPSR1LMNAALDH1A1TDP1CYP2C9 | |
| SCHEMBL17870954 | 0.75 | ALDH1A1 (0.40) | LMNAPOLBALDH1A1TDP1CYP2C9 | |
| Methacrylic Acid SCHEMBL5083136 | 0.74 | LMNA (0.46) | LMNAPOLBALDH1A1TDP1CYP2C9 | |
| Hydrochloric Acid SCHEMBL4867848 | 0.74 | HDAC3 (0.37) | LMNAALDH1A1HTTKDM4EL3MBTL1 | |
| Butane SCHEMBL27630383 | 0.74 | GAA (0.52) | LMNAALDH1A1TDP1CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3236918-A1 | USE OF A FATTY ACID ESTER FOR MATTIFYING THE SKIN AND COMPOSITION COMPRISING THIS ESTER | L'OREAL (FR) | 2017-11-01 | — | — | EP | disclosed |
| WO-2016102695-A1 | USE OF A FATTY ACID ESTER FOR MATTIFYING THE SKIN AND COMPOSITION COMPRISING THIS ESTER | L'OREAL (FR) | 2016-06-30 | — | — | WO | disclosed |