SCHEMBL17875595

SCHEMBL17875595

CCc1ccc2c(c1)OCN(c1cc(C)cc(C)c1)C2

nearest known ligand 0.44

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
VDR P11473 1/20 0.36
PARP1 P09874 1/20 0.31
KCNQ2 O43526 1/20 0.31
ACLY P53396 1/20 0.31
GAA P10253 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17875600 0.89 MAPT (0.44) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL17875596 0.84 MAPT (0.50) MAPTALDH1A1NPC1RAB9AVDR
SCHEMBL17875589 0.80 VDR (0.44) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL19501007 0.78 MAPT (0.64) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL17875593 0.77 VDR (0.53) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL15297298 0.72 VDR (0.56) MAPTALDH1A1NPC1RAB9AVDR
SCHEMBL12162801 0.72 RAB9A (0.66) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL17875592 0.72 VDR (0.47) MAPTALDH1A1KDM4ENPC1RAB9A
SCHEMBL17875591 0.69 MAPT (0.44) MAPTALDH1A1VDRACLYGAA
SCHEMBL17875597 0.69 MAPT (0.44) MAPTALDH1A1VDRACLYGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC 2023-05-04 US disclosed
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC 2023-05-04 US disclosed
US-11566106-B2 Composite materials containing benzoxazines and method for making the same CYTEC INDUSTRIES INC. (US) 2023-01-31 US disclosed
US-20200291179-A1 COMPOSITE MATERIALS CONTAINING BENZOXAZINES AND METHOD FOR MAKING THE SAME CYTEC INDUSTRIES INC. (US) 2020-09-17 US disclosed
EP-3240829-B1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC IND INC (US) 2019-08-21 EP disclosed
US-20160185908-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC. (US) 2016-06-30 US disclosed
US-20160185908-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME CYTEC INDUSTRIES INC. (US) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200291179-A1 COMPOSITE MATERIALS CONTAINING BENZOXAZINES AND METHOD FOR MAKING THE SAME F12, COL1A1, BRIX1 MAPT 2756/4885ALDH1A1 1216/4885KDM4E 1494/4885
US-11566106-B2 Composite materials containing benzoxazines and method for making the same F12, COL1A1, BRIX1 MAPT 2756/4885ALDH1A1 1216/4885KDM4E 1494/4885
US-20230133556-A1 BENZOXAZINES AND COMPOSITIONS CONTAINING THE SAME F12, BRIX1, COL1A1 MAPT 2194/4885ALDH1A1 1160/4885KDM4E 1267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.