SCHEMBL17876001

SCHEMBL17876001

O=S1(=O)Cc2ccc(-c3cc(-c4cccnc4)cc(-c4cccnc4)c3)cc2-c2cc(-c3ccc4oc5ccccc5c4c3)ccc2C1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.41
TDP2 O95551 2/20 0.41
CYP1A2 P05177 6/20 0.39
CYP3A4 P08684 5/20 0.39
LMNA P02545 3/20 0.39
MAPK1 P28482 3/20 0.39
CYP2D6 P10635 2/20 0.39
CLK4 Q9HAZ1 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MEN1 O00255 1/20 0.39
ALOX15 P16050 1/20 0.39
KMT2A Q03164 1/20 0.39
CYP11B1 P15538 7/20 0.39
CYP11B2 P19099 7/20 0.39
CYP19A1 P11511 3/20 0.39
PIM1 P11309 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
CYP2C9 P11712 3/20 0.38
CYP2C19 P33261 2/20 0.38
PIK3CA P42336 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17875970 0.96 CYP11B1 (0.41) PGRTDP2CYP1A2CYP3A4LMNA
SCHEMBL17875946 0.96 CYP11B1 (0.41) PGRTDP2CYP1A2CYP3A4LMNA
SCHEMBL17875997 0.94 CYP19A1 (0.41) PGRTDP2CYP1A2CYP3A4ALDH1A1
SCHEMBL17875937 0.90 CYP11B1 (0.41) PGRTDP2CYP1A2CYP3A4ALDH1A1
SCHEMBL17875968 0.90 CYP11B1 (0.41) PGRTDP2CYP1A2CYP3A4ALDH1A1
SCHEMBL17876007 0.89 PGR (0.39) PGRTDP2CYP1A2CYP3A4LMNA
SCHEMBL17875993 0.88 ALOX5 (0.43) PGRTDP2CYP1A2CYP3A4CYP11B1
SCHEMBL17876003 0.88 PLA2G2A (0.44) PGRCYP3A4LMNACLK4ALDH1A1
SCHEMBL17876000 0.86 KMT2A (0.45) CYP1A2CYP3A4LMNAMAPK1CYP2D6
SCHEMBL17875902 0.86 CYP11B1 (0.41) PGRTDP2CYP1A2CYP3A4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 PGR 1766/4885TDP2 3979/4885CYP1A2 757/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 PGR 1766/4885TDP2 3979/4885CYP1A2 757/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.