SCHEMBL17876158

SCHEMBL17876158

CC1(C)Oc2cc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)ccc2-c2cc(-c3ccc4oc5ccccc5c4c3)ccc2O1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.40
PLA2G4A P47712 4/20 0.40
PLA2G10 O15496 1/20 0.38
HSP90AA1 P07900 1/20 0.35
HSP90AB1 P08238 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
NPC1 O15118 1/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
PGR P06401 2/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
KIF11 P52732 1/20 0.33
L3MBTL1 Q9Y468 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876141 1.00 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL17876201 0.95 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL17876150 0.94 MAPT (0.40) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL17876159 0.93 MMP12 (0.38) PLA2G2APLA2G4APLA2G10KDM4EMEN1
SCHEMBL17876139 0.93 MMP12 (0.38) PLA2G2APLA2G4APLA2G10KDM4EMEN1
SCHEMBL17876140 0.90 PGR (0.38) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL17876177 0.90 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL17876153 0.90 PLA2G2A (0.34) PLA2G2APLA2G4APLA2G10HSP90AA1HSP90AB1
SCHEMBL17876148 0.89 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10MEN1NPC1
SCHEMBL17876170 0.89 PLA2G2A (0.35) PLA2G2APLA2G4APLA2G10MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 PLA2G2A 4359/4885PLA2G4A 4087/4885PLA2G10 4067/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 PLA2G2A 4359/4885PLA2G4A 4087/4885PLA2G10 4067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.