SCHEMBL17876208

SCHEMBL17876208

CC1(C)Oc2ccc(-c3cc(-c4ccccc4)cc(-c4ccccc4)c3)cc2-c2cc(-c3cccc4oc5ccccc5c34)ccc2O1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.38
PLA2G4A P47712 4/20 0.38
ALOX5 P09917 1/20 0.37
PLA2G10 O15496 1/20 0.36
PGR P06401 2/20 0.32
PRKDC P78527 2/20 0.32
ALDH1A1 P00352 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAPT P10636 1/20 0.32
MMP12 P39900 1/20 0.31
MMP13 P45452 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31
HPGD P15428 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KIF11 P52732 1/20 0.31
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17876170 0.96 PLA2G2A (0.35) PLA2G2APLA2G4AALOX5PLA2G10PGR
SCHEMBL17876148 0.96 PLA2G2A (0.35) PLA2G2APLA2G4AALOX5PLA2G10PGR
SCHEMBL17876207 0.93 ALOX5 (0.42) ALOX5PGRALDH1A1L3MBTL1MAPT
SCHEMBL17876202 0.90 HSP90AA1 (0.39) PLA2G2APLA2G4AALOX5PLA2G10PGR
SCHEMBL17876199 0.90 ALOX5 (0.39) ALOX5PGRPRKDCALDH1A1L3MBTL1
SCHEMBL17876209 0.90 ALOX5 (0.34) PLA2G2APLA2G4AALOX5PLA2G10ALDH1A1
SCHEMBL17876206 0.88 BACE1 (0.44) ALOX5PGRALDH1A1MAPTHPGD
SCHEMBL17876192 0.88 ALOX5 (0.51) PLA2G2APLA2G4AALOX5PLA2G10PRKDC
SCHEMBL17876149 0.88 ALOX5 (0.39) ALOX5PGRALDH1A1L3MBTL1MAPT
SCHEMBL17876200 0.88 MMP12 (0.40) PLA2G2APLA2G4APLA2G10PGRPRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-03-03 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10581000-B2 Condensed cyclic compound and organic light-emitting device including the same CRY1, CRY2, CCNE2 PLA2G2A 4359/4885PLA2G4A 4087/4885ALOX5 3059/4885
US-20160190482-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 PLA2G2A 4359/4885PLA2G4A 4087/4885ALOX5 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.