Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.33 |
| ▸ | IGF1R | P08069 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | SRC | P12931 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | PLK1 | P53350 | 2/20 | 0.33 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | NEK2 | P51955 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17876379 | 0.86 | MEN1 (0.34) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL8310257 | 0.69 | ALOX15 (0.44) | HPGDKDM4EADORA3ALDH2SMN1; SMN2 | |
| SCHEMBL11315028 | 0.66 | KMT2A (0.43) | HPGDKDM4EADORA3MEN1NPC1 | |
| SCHEMBL29800692 | 0.65 | PIM1 (0.73) | ALDH1A1HPGDHSD17B10KDM4EADORA3 | |
| SCHEMBL17525029 | 0.63 | ALDH2 (0.59) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL11851931 | 0.60 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10KDM4EMAPK1 | |
| SCHEMBL16477275 | 0.60 | MAOA (0.61) | ALDH1A1HPGDHSD17B10KDM4ECASP1 | |
| SCHEMBL29769730 | 0.59 | KDM4E (0.48) | ALDH1A1HPGDHSD17B10KDM4ENUAK1 | |
| SCHEMBL28726401 | 0.59 | KDM4E (0.48) | ALDH1A1HPGDHSD17B10KDM4ENUAK1 | |
| SCHEMBL28726451 | 0.59 | KDM4E (0.48) | ALDH1A1HPGDHSD17B10KDM4ENUAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185745-A1 | ANALOGS OF VINAXANTHONE AND XANTHOFULVIN, METHODS OF SYNTHESIS, AND METHODS OF TREATMENTS THEREOF | VAT1, NQO1, VARS1 | ALDH1A1 2380/4885HPGD 51/4885HSD17B10 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.