SCHEMBL1787816

SCHEMBL1787816

CCOC(=O)C(C)C(CCC(F)(F)F)C(=O)OCC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.35
ALDH1A1 P00352 3/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.31
ALOX15 P16050 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
SOAT1 P35610 1/20 0.31
MMP8 P22894 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CPB2 Q96IY4 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TP53 P04637 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
AAK1 Q2M2I8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19465643 0.88 ALDH1A1 (0.39) POLBALDH1A1LMNAHSD17B10HTT
SCHEMBL28450302 0.85 POLB (0.35) POLBALDH1A1LMNAHSD17B10HPGD
SCHEMBL1785179 0.84 TSHR (0.36) ALDH1A1HTTGAASMN1; SMN2
SCHEMBL28313252 0.83 RAB9A (0.32)
SCHEMBL1785121 0.82 HTT (0.37) HTTAAK1
SCHEMBL28342794 0.82 NAAA (0.40) ALDH1A1TP53
SCHEMBL27985135 0.77 CA2 (0.41) POLBALDH1A1LMNAHSD17B10CPB2
SCHEMBL8157644 0.76 TDP1 (0.42) POLBALDH1A1LMNAHSD17B10HTT
SCHEMBL8980113 0.76 ALDH1A1 (0.42) POLBALDH1A1LMNAHSD17B10HPGD
SCHEMBL27237567 0.74 TSHR (0.34) ALDH1A1GAASMN1; SMN2AAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3397657-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2024-06-12 EP claimed
EP-3135699-B1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME CHINA PETROLEUM & CHEM CORP (CN) 2021-07-21 EP claimed
US-10633463-B2 Non-phthalate catalyst system and its use in the polymerization of olefins BRASKEM AMERICA, INC. (US) 2020-04-28 US claimed
US-10184017-B2 Catalyst component for propene polymerization, preparation method thereof, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-01-22 US claimed
US-20190010258-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. 2019-01-10 US claimed
EP-3397657-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS Braskem America, Inc. (US) 2018-11-07 EP claimed
WO-2017117433-A1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA, INC. (US) 2017-07-06 WO claimed
EP-3135699-A1 CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION, PREPARATION METHOD THEREFOR AND CATALYST HAVING SAME China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
US-20170044280-A1 Catalyst Component for Propene Polymerization, Preparation Method Thereof, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-02-16 US claimed
CN-104558286-A Catalyst component for olefin polymerization and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558287-A Catalyst component for olefin polymerization as well as catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
US-20260015443-A1 POLYPROPLYENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING THE SAME EXXONMOBIL CHEMICAL PATENTS INC. (US) 2026-01-15 US disclosed
WO-2025020304-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST 中国石油天然气股份有限公司 2025-01-30 WO disclosed
US-20240209125-A1 PREPOLYMERIZED CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2024-06-27 US disclosed
EP-3397657-B1 NON-PHTHALATE CATALYST SYSTEM AND ITS USE IN THE POLYMERIZATION OF OLEFINS BRASKEM AMERICA INC (US) 2024-06-12 EP disclosed
WO-2004087807-A1 IMPACT RESISTANT POLYOLEFIN COMPOSITIONS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2004-10-14 WO disclosed
WO-2004024785-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-03-25 WO disclosed
WO-2004005359-A1 CATALYST SYSTEM FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-01-15 WO disclosed
EP-1088009-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Basell Technology Company B.V. (NL) 2001-04-04 EP disclosed
WO-2000063261-A1 COMPONENTS AND CATALYSTS FOR THE POLYMERIZATION OF OLEFINS BASELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015443-A1 POLYPROPLYENE COMPOSITIONS WITH ENHANCED STRAIN HARDENING AND METHODS OF PRODUCING THE SAME PFN1, PSD, FDFT1 POLB 776/4885ALDH1A1 3138/4885LMNA 1185/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.