Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 12/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17878854 | 0.89 | MCHR1 (0.43) | ENPP2CYP19A1MAPT | |
| SCHEMBL17730237 | 0.89 | USP2 (0.35) | ENPP2MAPT | |
| SCHEMBL17878849 | 0.89 | MCHR1 (0.43) | ENPP2CYP19A1MAPT | |
| SCHEMBL17878978 | 0.88 | MCHR1 (0.40) | MAPTGAA | |
| SCHEMBL21281383 | 0.88 | MCHR1 (0.40) | MAPTGAA | |
| SCHEMBL17878857 | 0.87 | USP2 (0.35) | ENPP2MAPT | |
| SCHEMBL17740880 | 0.87 | ENPP2 (0.41) | ENPP2S1PR5MAPT | |
| SCHEMBL17878868 | 0.85 | ENPP2 (0.34) | ENPP2MAPT | |
| SCHEMBL17878879 | 0.85 | CARM1 (0.36) | MAPT | |
| SCHEMBL17878873 | 0.82 | LDHA (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240065302-A1 | SWEETENER COMPOSITIONS COMPRISING MOGROSIDES AND USES THEREOF | FIRMENICH INCORPORATED | 2024-02-29 | — | — | US | disclosed |
| US-11339128-B2 | Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers | FIRMENICH INCORPORATED (US) | 2022-05-24 | — | — | US | disclosed |
| US-20180086751-A1 | SWEETENER COMPOSITION | SENOMYX, INC. | 2018-03-29 | — | — | US | disclosed |
| US-20160185727-A1 | SUBSTITUTED 4-AMINO-5-(CYCLOHEXYLOXY)QUINOLINE-3-CARBOXYLIC ACIDS AS SWEET FLAVOR MODIFIERS | FIRMENICH INCORPORATED | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339128-B2 | Substituted 4-amino-5-(cyclohexyloxy)quinoline-3-carboxylic acids as sweet flavor modifiers | TAS2R5, TAS2R4, TAS2R30 | ENPP2 2528/4885S1PR5 2622/4885CYP19A1 4656/4885 |
| US-20180086751-A1 | SWEETENER COMPOSITION | TAS2R50, TAS1R2, TAS2R10 | ENPP2 3108/4885S1PR5 855/4885CYP19A1 3565/4885 |
| US-20160185727-A1 | SUBSTITUTED 4-AMINO-5-(CYCLOHEXYLOXY)QUINOLINE-3-CARBOXYLIC ACIDS AS SWEET FLAVOR MODIFIERS | TAS2R5, TAS2R4, TAS2R30 | ENPP2 2528/4885S1PR5 2622/4885CYP19A1 4656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.