SCHEMBL17879130

SCHEMBL17879130

c1ccc(N(c2ccccc2)c2ccc(-c3cc4nc5nc6cc7nc8nc(-c9ccc(N(c%10ccccc%10)c%10ccccc%10)cc9)c(-c9ccc(N(c%10ccccc%10)c%10ccccc%10)cc9)nc8cc7nc6nc5nc4cc3-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 1/20 0.39
KDM4E B2RXH2 5/20 0.36
ALDH1A1 P00352 4/20 0.36
L3MBTL1 Q9Y468 4/20 0.36
KMT2A Q03164 3/20 0.36
ATM Q13315 1/20 0.36
TLR9 Q9NR96 1/20 0.36
ADK P55263 2/20 0.35
HTT P42858 2/20 0.35
RXFP1 Q9HBX9 1/20 0.35
LMNA P02545 3/20 0.34
GAA P10253 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 2/20 0.34
HPGD P15428 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
PDE10A Q9Y233 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879123 0.93 PSMB5 (0.40) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL12146794 0.87 PSMB5 (0.49) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL12146795 0.85 PSMB5 (0.48) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL6725426 0.85 PSMB5 (0.48) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL6726086 0.85 PSMB5 (0.48) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL12146790 0.84 PSMB5 (0.49) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL12146789 0.84 PSMB5 (0.49) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL17879128 0.83 ALDH1A1 (0.47) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL18216994 0.82 ALDH1A1 (0.46) PSMB5KDM4EALDH1A1L3MBTL1KMT2A
SCHEMBL17879120 0.82 TDP1 (0.45) KDM4EALDH1A1L3MBTL1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210074927-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2021-03-11 US disclosed
US-10862047-B2 Organic electroluminescent device KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2020-12-08 US disclosed
US-10658596-B2 2020-05-19 US disclosed
US-10600983-B2 Organic electroluminescent device comprising delayed fluorescent materials KYULUX, INC. (JP) 2020-03-24 US disclosed
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound KYULUX, INC. (JP) 2020-02-11 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND KYULUX, INC. (JP) 2017-10-05 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND KYULUX, INC. (JP) 2017-07-27 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20170163010-A1 ORGANIC LIGHT-EMITTING ELEMENT KYUSHU UNIVERSITY NATIONAL UNIVERSITY CORPORATION (JP) 2017-06-08 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160329512-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYULUX, INC. (JP) 2016-11-10 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed
US-20160190478-A1 ORGANIC ELECTROLUMINESCENT DEVICE KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170288146-A1 HOST MATERIAL FOR DELAYED FLUORESCENT MATERIALS, ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND TERB1, TERT, TCOF1 PSMB5 987/4885KDM4E 3804/4885ALDH1A1 2419/4885
US-10559757-B2 Host material for delayed fluorescent materials, organic light-emitting device and compound TERB1, TERT, TCOF1 PSMB5 987/4885KDM4E 3804/4885ALDH1A1 2419/4885
US-20170213974-A1 ORGANIC LIGHT-EMITTING DEVICE, HOST MATERIAL, LIGHT-EMITTING MATERIAL, AND COMPOUND CRY1, CRY2, CYBA PSMB5 1364/4885KDM4E 2784/4885ALDH1A1 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.