SCHEMBL17879456

SCHEMBL17879456

c1ccc(-c2ccc3c(c2)c2cc(-c4ccccc4)ccc2n3-c2cccc3c2-c2ccccc2C32c3ccccc3-c3c2ccc2c3oc3ccccc32)cc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.36
PRKDC P78527 2/20 0.34
PLA2G2A P14555 3/20 0.32
PLA2G4A P47712 3/20 0.32
PLA2G10 O15496 1/20 0.31
GGPS1 O95749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20232199 0.88 ALOX5 (0.40) ALOX5PRKDCGGPS1
SCHEMBL16491646 0.87 ALOX5 (0.33) ALOX5PRKDCPLA2G2APLA2G4AGGPS1
SCHEMBL20232354 0.87 ALOX5 (0.34) ALOX5PRKDC
SCHEMBL21388924 0.86 PLA2G2A (0.34) PRKDCPLA2G2APLA2G4APLA2G10
SCHEMBL24434085 0.86 ALOX5 (0.38) ALOX5PRKDCGGPS1
SCHEMBL20129501 0.86 ALOX5 (0.31) ALOX5PRKDC
SCHEMBL16491768 0.86
SCHEMBL16810661 0.85 ALOX5 (0.44) ALOX5PRKDCGGPS1
SCHEMBL23138915 0.85 ALOX5 (0.37) ALOX5PRKDCGGPS1
SCHEMBL20129505 0.85 ALOX5 (0.32) ALOX5PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10665790-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2020-05-26 US disclosed
US-9978950-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-05-22 US disclosed
US-9978950-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2018-05-22 US disclosed
EP-3033405-B1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-05-09 EP disclosed
US-9837617-B2 Materials for electronic devices MERCK PATENT GMBH (DE) 2017-12-05 US disclosed
US-20170301865-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-10-19 US disclosed
US-20170301865-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-10-19 US disclosed
US-20160190466-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-30 US disclosed
US-20160190466-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2016-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10665790-B2 Materials for electronic devices SDHB, SDHA, ETFB ALOX5 3759/4885PRKDC 4064/4885PLA2G2A 4713/4885
US-20160190466-A1 MATERIALS FOR ELECTRONIC DEVICES SDHB, SDHA, ETFB ALOX5 3759/4885PRKDC 4064/4885PLA2G2A 4713/4885
US-20170301865-A1 MATERIALS FOR ELECTRONIC DEVICES SDHB, SDHA, ETFB ALOX5 3759/4885PRKDC 4064/4885PLA2G2A 4713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.