SCHEMBL17880388

SCHEMBL17880388

Brc1cc(Br)cc(-c2ccncc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
LMNA P02545 2/20 0.58
NOTUM Q6P988 1/20 0.48
CYP17A1 P05093 3/20 0.46
CYP21A2 P08686 3/20 0.46
CYP11B1 P15538 3/20 0.46
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
QDPR P09417 1/20 0.43
S1PR1 P21453 1/20 0.41
S1PR3 Q99500 1/20 0.41
KIF11 P52732 2/20 0.41
IMPDH2 P12268 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
PABPC1 P11940 1/20 0.39
APOBEC3A P31941 1/20 0.39
EIF4H Q15056 1/20 0.39
APOBEC3G Q9HC16 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14884178 0.95 MAPT (0.58) MAPTLMNANOTUMCYP17A1CYP21A2
Biphenyl SCHEMBL28049848 0.91 NOTUM (0.65) MAPTLMNANOTUMRAB9ANPC1
SCHEMBL16284630 0.86 NOTUM (0.52) MAPTLMNANOTUMCYP17A1CYP21A2
SCHEMBL23714949 0.84 NPC1 (0.47) MAPTLMNANOTUMCYP17A1CYP21A2
SCHEMBL25791319 0.84 MAPT (0.46) MAPTLMNANOTUMCYP17A1CYP21A2
SCHEMBL17922975 0.84 LMNA (0.46) MAPTLMNANOTUMCYP17A1CYP21A2
SCHEMBL505073 0.84 CYP17A1 (0.60) MAPTLMNANOTUMCYP17A1CYP21A2
SCHEMBL22534596 0.83 RAB9A (0.49) MAPTLMNANOTUMRAB9ANPC1
SCHEMBL22534702 0.83 RAB9A (0.49) MAPTLMNANOTUMRAB9ANPC1
SCHEMBL22534627 0.81 RAB9A (0.47) MAPTLMNANOTUMCYP17A1CYP21A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230240131-A1 LIGHT EMITTING ELEMENT AND ORGANOMETALLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240131-A1 LIGHT EMITTING ELEMENT AND ORGANOMETALLIC COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
CN-104693218-B Organic light emitting diode material as well as preparation method and application thereof 中节能万润股份有限公司 2017-01-18 CN disclosed
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-9461272-B2 Organic light emitting device including light-efficiency improvement layer SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-04 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
US-20160190516-A1 ORGANIC LIGHT EMITTING DEVICE INCLUDING LIGHT-EFFICIENCY IMPROVEMENT LAYER SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-30 US disclosed
CN-104693218-A Organic light emitting diode material as well as preparation method and application thereof YANTAI VALIANT FINE CHEMICALS CO LTD 2015-06-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240131-A1 LIGHT EMITTING ELEMENT AND ORGANOMETALLIC COMPOUND FOR THE SAME LAGE3, NFE2L2, EML4 MAPT 1132/4885LMNA 1928/4885NOTUM 2843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.