Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | PRKCG | P05129 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 1/20 | 0.45 |
| ▸ | PRKCH | P24723 | 1/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.45 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.45 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.45 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.34 |
| ▸ | IGF2R | P11717 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20725164 | 0.81 | TLR4 (0.39) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL17867745 | 0.78 | LGALS8 (0.33) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL17866072 | 0.77 | ALDH1A1 (0.41) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL16155658 | 0.75 | ALDH1A1 (0.33) | TLR4ALDH1A1 | |
| SCHEMBL17867763 | 0.75 | ALDH1A1 (0.33) | TLR4ALDH1A1 | |
| SCHEMBL14667225 | 0.75 | L3MBTL1 (0.42) | TLR4ALDH1A1THRBGAA | |
| SCHEMBL14667222 | 0.75 | L3MBTL1 (0.42) | TLR4ALDH1A1THRBGAA | |
| SCHEMBL16561877 | 0.74 | CYP2D6 (0.49) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL17683644 | 0.74 | CYP2D6 (0.49) | TLR4PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL17695748 | 0.74 | CYP2D6 (0.49) | TLR4PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220023326-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | UNIV TEXAS (US) | 2022-01-27 | — | — | US | disclosed |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2016-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160184336-A1 | ESTERS OF 2-DEOXY-MONOSACHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | DERA, G6PD, HK2 | TLR4 3721/4885PRKD3 1925/4885PRKCG 2392/4885 |
| US-20220023326-A1 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | SLC2A2, SLC2A1, SLC2A4 | TLR4 3754/4885PRKD3 1796/4885PRKCG 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.