Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.40 |
| ▸ | KLK1 | P06870 | 2/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412543 | 0.69 | HDAC6 (0.44) | HDAC6HDAC1HDAC3HDAC8KDM1A | |
| SCHEMBL12017424 | 0.69 | RAB9A (0.64) | HDAC6HDAC1HDAC3HRH3TSHR | |
| SCHEMBL12321407 | 0.69 | ENPP2 (0.46) | HDAC6TSHRALDH1A1LMNAMAPT | |
| SCHEMBL3738805 | 0.68 | PIK3CA (0.65) | MAPK14NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL18330480 | 0.68 | OGA (0.46) | HRH3ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30576121 | 0.66 | MAPK14 (0.52) | MAPK14NPC1RAB9ALMNAMAPT | |
| SCHEMBL30576044 | 0.64 | HTR1F (0.57) | MAPK14NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4190388 | 0.64 | ALDH1A1 (0.47) | HRH3ALDH1A1LMNA | |
| SCHEMBL30576117 | 0.63 | RAF1 (0.48) | MAPK14NPC1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30576128 | 0.63 | MAPT (0.55) | MAPK14NPC1ALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382197-B2 | Substituted hydroxamic acids and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-07-05 | — | — | US | claimed |