Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | WNT1 | P04628 | 3/20 | 0.47 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.45 |
| ▸ | CLK3 | P49761 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30576044 | 0.91 | HTR1F (0.57) | MAPK14NPC1RXRARAB9ADYRK1A | |
| SCHEMBL30576180 | 0.91 | POLB (0.47) | MAPK14NPC1POLBRXRARAB9A | |
| SCHEMBL30576117 | 0.89 | RAF1 (0.48) | MAPK14NPC1RXRADYRK1AGSK3B | |
| SCHEMBL30576128 | 0.89 | MAPT (0.55) | MAPK14NPC1POLBRAB9ADYRK1A | |
| SCHEMBL30576020 | 0.87 | MAPK14 (0.47) | MAPK14NPC1RXRARAB9ADYRK1A | |
| SCHEMBL30576035 | 0.87 | RXRA (0.46) | MAPK14NPC1RXRADYRK1AGSK3B | |
| SCHEMBL30576067 | 0.85 | MALT1 (0.49) | MAPK14DYRK1AGSK3BWNT1HTR1F | |
| SCHEMBL30576040 | 0.83 | PROKR1 (0.48) | MAPK14NPC1POLBRAB9AGSK3B | |
| SCHEMBL30576073 | 0.81 | RAB9A (0.56) | MAPK14RXRARAB9ADYRK1AGSK3B | |
| SCHEMBL30576056 | 0.81 | F2 (0.49) | MAPK14NPC1RXRARAB9ADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116836153-B | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-116836153-A | CDK9-Cyclin T1 protein interaction inhibitor and application thereof | 厦门大学 | 2023-10-03 | — | — | CN | disclosed |