Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17895972 | 0.90 | — | — | |
| Trifluoroacetic Acid SCHEMBL17895773 | 0.85 | CRHBP (0.35) | CRHBPCRHR2HIF1ATP53MAPT | |
| SCHEMBL17896285 | 0.83 | CRHBP (0.38) | CRHBPCRHR2HIF1ATP53MAPT | |
| SCHEMBL17895988 | 0.79 | CHRM2 (0.40) | — | |
| SCHEMBL17896001 | 0.79 | ALDH1A1 (0.37) | CRHBPCRHR2HIF1ATP53MAPT | |
| Hydrochloric Acid SCHEMBL17895974 | 0.78 | ALDH1A1 (0.37) | CRHBPCRHR2HIF1ATP53MAPT | |
| Trifluoroacetic Acid SCHEMBL17895971 | 0.75 | LMNA (0.30) | MAPT | |
| SCHEMBL17895779 | 0.73 | LMNA (0.34) | MAPT | |
| SCHEMBL17895905 | 0.72 | LMNA (0.34) | MAPT | |
| SCHEMBL17895899 | 0.72 | LMNA (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | claimed |
| WO-2016109706-A1 | FUSED POLYCYCLIC 2-PYRIDINONE ANTIBACTERIAL COMPOUNDS | PTC THERAPEUTICS, INC. (US) | 2016-07-07 | — | — | WO | disclosed |