Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.57 |
| ▸ | ACHE | P22303 | 12/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786901 | 0.85 | DRD2 (0.64) | DRD2DRD4ACHECHRM3BCHE | |
| Hydrochloric Acid SCHEMBL1786844 | 0.81 | ACHE (0.69) | DRD2DRD4ACHECHRM3BCHE | |
| SCHEMBL4209884 | 0.78 | KDM4E (0.65) | DRD2DRD4KDM4EPKM | |
| SCHEMBL29201760 | 0.78 | CHRM4 (0.60) | DRD2DRD4CHRM3CHRM4KDM4E | |
| SCHEMBL6807533 | 0.78 | MAPK14 (0.53) | DRD4KDM4EPKM | |
| SCHEMBL7849387 | 0.78 | GPR119 (0.55) | DRD2DRD4CHRM4 | |
| SCHEMBL31162867 | 0.77 | NR1H2 (0.57) | CHRM4 | |
| SCHEMBL8478310 | 0.77 | GPR119 (0.57) | ACHECHRM3BCHEMAOBCHRM4 | |
| SCHEMBL7848865 | 0.77 | CHRM4 (0.47) | ACHECHRM4KDM4EPKM | |
| SCHEMBL7847033 | 0.77 | GPR119 (0.61) | ACHEBCHEMAOBCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326625-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2011-06-01 | — | — | EP | disclosed |
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-26 | — | — | US | disclosed |
| WO-2010007382-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HSTAMINE H3 ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED. (JP) | 2010-01-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124626-A1 | BENZAZEPINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 ANTAGONISTS | HRH4, HRH3, HRH2 | DRD2 79/4885DRD4 243/4885ACHE 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.