SCHEMBL17899642 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	1/20	0.39

▸	USP9X	Q93008	4/20	0.39

▸	EPHX2	P34913	1/20	0.37

▸	PKM	P14618	4/20	0.36

▸	MEN1	O00255	3/20	0.35

▸	KMT2A	Q03164	3/20	0.35

▸	LMNA	P02545	4/20	0.35

▸	ALDH1A1	P00352	2/20	0.35

▸	POLB	P06746	1/20	0.35

▸	CHRM5	P08912	1/20	0.35

▸	HTT	P42858	1/20	0.34

▸	CYP2C19	P33261	1/20	0.34

▸	GAA	P10253	2/20	0.34

▸	ALOX15	P16050	1/20	0.34

▸	MAPK1	P28482	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19472043	0.92	EPHX2 (0.36)	MAPTUSP9XEPHX2PKMMEN1
SCHEMBL17899644	0.90	MAPT (0.48)	MAPTUSP9XEPHX2PKMMEN1
SCHEMBL17899690	0.84	ALDH1A1 (0.46)	MAPTEPHX2PKMKMT2ALMNA
SCHEMBL17899697	0.82	LMNA (0.43)	MAPTEPHX2PKMMEN1KMT2A
SCHEMBL17899649	0.82	KMT2A (0.41)	MAPTEPHX2PKMMEN1KMT2A
SCHEMBL17897332	0.82	EPHX2 (0.41)	EPHX2KMT2AALDH1A1GAAMAPK1
SCHEMBL17899639	0.82	PKM (0.43)	MAPTEPHX2PKMMEN1KMT2A
SCHEMBL17899640	0.82	GAA (0.42)	EPHX2MEN1KMT2AALDH1A1GAA
SCHEMBL17899686	0.81	EPHX2 (0.44)	EPHX2MEN1KMT2AALDH1A1HTT
SCHEMBL17899688	0.81	ALDH1A1 (0.46)	PKMMEN1KMT2AALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2016107544-A1	INTERMEDIATE COMPOUND FOR PREPARING PYRROLE AMIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF	成都先导药物开发有限公司	2016-07-07	—	—	WO	disclosed