SCHEMBL17899645

SCHEMBL17899645

Cc1cc(S(=O)(=O)N2CC=C(C(=O)NOC3CCCCO3)C2)ccc1-c1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ATR Q13535 1/20 0.37
OXTR P30559 2/20 0.37
AVPR1A P37288 2/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
GFER P55789 1/20 0.36
KMT2A Q03164 3/20 0.36
PKM P14618 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ATM Q13315 1/20 0.35
CYP3A4 P08684 1/20 0.35
KDM4E B2RXH2 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899687 0.92 KMT2A (0.37) OXTRAVPR1AALDH1A1MAPTKMT2A
SCHEMBL17899699 0.89 KMT2A (0.39) ATRKMT2APKMTDP1MEN1
SCHEMBL17899649 0.88 KMT2A (0.41) MAPTKMT2APKMTDP1MEN1
SCHEMBL17899688 0.83 ALDH1A1 (0.46) ALDH1A1KMT2APKMTSHRMEN1
SCHEMBL17899697 0.83 LMNA (0.43) ALDH1A1LMNAMAPTKMT2APKM
SCHEMBL17899686 0.81 EPHX2 (0.44) ALDH1A1KMT2AMEN1
SCHEMBL17897429 0.81 PKM (0.43) ATRALDH1A1LMNAMAPTGFER
SCHEMBL17899665 0.81 KMT2A (0.44) ALDH1A1LMNAMAPTKMT2AMEN1
SCHEMBL17899690 0.81 ALDH1A1 (0.46) ALDH1A1LMNAMAPTKMT2APKM
SCHEMBL17899692 0.81 PKM (0.46) ALDH1A1LMNAKMT2APKMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016107544-A1 INTERMEDIATE COMPOUND FOR PREPARING PYRROLE AMIDE COMPOUND AND PREPARATION METHOD AND USE THEREOF 成都先导药物开发有限公司 2016-07-07 WO disclosed