Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17905183 | 1.00 | CTSK (0.43) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17904998 | 1.00 | CTSK (0.43) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17895086 | 0.93 | NR3C1 (0.42) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17895088 | 0.93 | NR3C1 (0.42) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17895087 | 0.93 | NR3C1 (0.42) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17900764 | 0.93 | CTSK (0.41) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17895332 | 0.92 | EPHX2 (0.39) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17895334 | 0.92 | EPHX2 (0.39) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17900551 | 0.92 | CTSK (0.42) | CTSKCTSSMAPTALDH1A1MEN1 | |
| SCHEMBL17895331 | 0.92 | EPHX2 (0.39) | CTSKCTSSMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255991-B1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-30 | — | — | EP | disclosed |
| EP-3240413-B1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | DOW AGROSCIENCES LLC (US) | 2019-10-08 | — | — | US | disclosed |
| US-10173981-B2 | Picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2019-01-08 | — | — | US | disclosed |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2018-01-04 | — | — | US | disclosed |
| WO-2016109305-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109288-A1 | USE OF PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109289-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016109304-A1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10433555-B2 | Picolinamide compounds with fungicidal activity | PFAS, CASP2, CYP1A2 | CTSK 2808/4885CTSS 1597/4885MAPT 1306/4885 |
| US-20180000080-A1 | PICOLINAMIDES AS FUNGICIDES | CYP1A2, CYP4F12, FKBP2 | CTSK 2728/4885CTSS 1587/4885MAPT 1756/4885 |
| US-20180002288-A1 | USE OF PICOLINAMIDES AS FUNGICIDES | PFAS, CYP1A2, CYP4F12 | CTSK 2817/4885CTSS 1293/4885MAPT 2243/4885 |
| US-10173981-B2 | Picolinamides as fungicides | CYP1A2, CYP4F12, FKBP2 | CTSK 2728/4885CTSS 1587/4885MAPT 1756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.