Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 10/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17901983 | 0.95 | ALDH1A1 (0.35) | ALDH1A1HSD11B1MEN1KMT2AMAPT | |
| SCHEMBL23227409 | 0.71 | MEN1 (0.37) | ALDH1A1HSD11B1MEN1KMT2AMAPT | |
| SCHEMBL2301177 | 0.70 | HSD11B1 (0.51) | HSD11B1 | |
| SCHEMBL24603324 | 0.70 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPTBRCA1 | |
| SCHEMBL2521564 | 0.70 | MEN1 (0.44) | ALDH1A1MEN1KMT2AMAPTBRCA1 | |
| SCHEMBL3080507 | 0.66 | HTR6 (0.41) | ALDH1A1MEN1KMT2AMAPTBRCA1 | |
| SCHEMBL3087078 | 0.66 | HTR6 (0.41) | ALDH1A1MEN1KMT2AMAPTBRCA1 | |
| SCHEMBL27163373 | 0.66 | GAA (0.41) | ALDH1A1MEN1KMT2AMAPTBRCA1 | |
| SCHEMBL18689264 | 0.66 | HTR6 (0.41) | ALDH1A1MEN1KMT2AMAPTBRCA1 | |
| SCHEMBL31207652 | 0.64 | MEN1 (0.45) | ALDH1A1HSD11B1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016106629-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |