Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14641753 | 0.71 | HSD11B1 (0.34) | MEN1MAPTBRCA1KMT2AATM | |
| SCHEMBL3069788 | 0.68 | ALDH1A1 (0.40) | MEN1MAPTBRCA1KMT2AATM | |
| SCHEMBL9963153 | 0.68 | HSD11B1 (0.35) | MEN1MAPTBRCA1KMT2AATM | |
| SCHEMBL23227409 | 0.68 | MEN1 (0.37) | MEN1MAPTBRCA1KMT2AATM | |
| SCHEMBL9265060 | 0.67 | — | — | |
| SCHEMBL2139086 | 0.67 | — | — | |
| SCHEMBL9265057 | 0.67 | — | — | |
| SCHEMBL9255482 | 0.67 | HSD11B1 (0.36) | MEN1MAPTBRCA1KMT2AATM | |
| SCHEMBL18122735 | 0.67 | LMNA (0.41) | MEN1MAPTBRCA1KMT2AATM | |
| SCHEMBL9260600 | 0.67 | GRM5 (0.40) | MEN1MAPTBRCA1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240543-B1 | BTK INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-11-06 | — | — | EP | disclosed |