Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MB | P02144 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17894453 | 1.00 | MIF (0.45) | MIFCYP17A1MAPTALDH1A1NR1H4 | |
| SCHEMBL18256797 | 1.00 | MIF (0.45) | MIFCYP17A1MAPTALDH1A1NR1H4 | |
| SCHEMBL10092627 | 0.92 | CYP17A1 (0.48) | CYP17A1NR1H4BRD4PSMB8L3MBTL1 | |
| SCHEMBL14155353 | 0.92 | CYP17A1 (0.48) | CYP17A1NR1H4BRD4PSMB8L3MBTL1 | |
| SCHEMBL13293398 | 0.89 | CYP17A1 (0.43) | CYP17A1ALDH1A1NR1H4CA12CA1 | |
| SCHEMBL13062960 | 0.89 | CYP17A1 (0.40) | CYP17A1MAPTALDH1A1NR1H4MEN1 | |
| SCHEMBL3777963 | 0.89 | CYP17A1 (0.40) | CYP17A1MAPTALDH1A1NR1H4MEN1 | |
| SCHEMBL3777965 | 0.89 | CYP17A1 (0.40) | CYP17A1MAPTALDH1A1NR1H4MEN1 | |
| SCHEMBL29803908 | 0.88 | MAP4K4 (0.40) | CYP17A1MAPTNR1H4MEN1CA1 | |
| SCHEMBL12049315 | 0.88 | CYP17A1 (0.40) | CYP17A1NR1H4PSMB8PTPN11MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230105108-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-04-06 | — | — | US | disclosed |
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2021-10-07 | — | — | US | disclosed |
| US-10980234-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC (US) | 2021-04-20 | — | — | US | disclosed |
| US-10779539-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | CORAL BAY II, LLC. (US) | 2020-09-22 | — | — | US | disclosed |
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | THE UNIVERSITY OF BATH (GB) | 2017-11-30 | — | — | US | disclosed |
| US-20170303541-A1 | ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2017-10-26 | — | — | US | disclosed |
| WO-2016108045-A2 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | SWANSEA UNIVERSITY (GB) | 2016-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170342025-A1 | ANTIMICROBIAL COMPOUNDS, COMPOSITIONS AND METHODS | ZYX, MPO, CFB | MIF 533/4885CYP17A1 1410/4885MAPT 4304/4885 |
| US-20210309641-A1 | AMIDINES AND AMIDINE ANALOGS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION ANTIBIOTICS | PAM, AMPD1, AMPD3 | MIF 1137/4885CYP17A1 4746/4885MAPT 4279/4885 |
| US-20170303541-A1 | ANTIMICROBIAL GUANIDINIUM AND THIOURONIUM FUNCTIONALIZED POLYMERS | PUF60, CAPG, GMPS | MIF 92/4885CYP17A1 4853/4885MAPT 1608/4885 |
| US-20230105108-A1 | COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND POTENTIATION OF ANTIBIOTICS | BPGM, MYD88, PGLS | MIF 767/4885CYP17A1 4493/4885MAPT 3202/4885 |
| US-10980234-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | MIF 92/4885CYP17A1 4853/4885MAPT 1608/4885 |
| US-11690380-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | MIF 92/4885CYP17A1 4853/4885MAPT 1608/4885 |
| US-10779539-B2 | Antimicrobial guanidinium and thiouronium functionalized polymers | PUF60, CAPG, GMPS | MIF 92/4885CYP17A1 4853/4885MAPT 1608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.