Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 14/20 | 0.71 |
| ▸ | TNKS2 | Q9H2K2 | 12/20 | 0.71 |
| ▸ | PARP1 | P09874 | 6/20 | 0.71 |
| ▸ | GUSB | P08236 | 7/20 | 0.71 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.71 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.64 |
| ▸ | WNT3A | P56704 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885282 | 0.87 | TNKS (0.93) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL6124189 | 0.84 | TNKS (0.93) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL258433 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL29592833 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL8618931 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL15775207 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL7765127 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL29764113 | 0.83 | TNKS (1.00) | TNKSTNKS2PARP1GUSBPARP2 | |
| Hydrochloric Acid SCHEMBL31529601 | 0.82 | TNKS (0.96) | TNKSTNKS2PARP1GUSBPARP2 | |
| SCHEMBL16965507 | 0.81 | TNKS (0.69) | TNKSTNKS2PARP1GUSBPARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058822-A1 | Method to alter or control the development and/or life cycle of various plant species | AMERICAN CYANAMID COMPANY (US) | 1982-09-01 | — | — | EP | claimed |
| EP-4583874-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024132001-A1 | MULTITARGET NUCLEAR RECEPTOR LIGANDS BASED ON 2-(4-(QUINOLIN-2-YLOXY)PHENOXY)PROPANOIC ACID AND 2-(4-(QUINOXALIN-2-YLOXY)PHENOXY)PROPANOIC ACID FOR THE TREATMENT OF METABOLIC AND LIVER DISEASES | CHARLES UNIVERSITY, FACULTY OF PHARMACY IN HRADEC KRALOVE (CZ) | 2024-06-27 | — | — | WO | disclosed |
| CN-115010671-B | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-115010671-A | One-step synthesis method of 2-substituted quinazolinone | 江苏大学 | 2022-09-06 | — | — | CN | disclosed |
| CN-106518789-B | A method of synthesis Quinazol derivative | 南京理工大学 | 2019-04-16 | — | — | CN | disclosed |
| CN-106518789-A | Method for synthesis of quinazolinone derivative | 南京理工大学 | 2017-03-22 | — | — | CN | disclosed |
| CN-106478525-A | A kind of method of synthesis quinazolone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |
| US-20120059002-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | HEPALINK (HONG KONG) LIMITED (HK) | 2012-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059002-A1 | NOVEL ANTI-INFLAMMATORY AGENTS | VCAM1, ICAM1, IL6 | TNKS 723/4885TNKS2 1458/4885PARP1 901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.