SCHEMBL17907470

SCHEMBL17907470

Cc1ccc(C)c(-c2cc(C(N)=O)ccc2C(N)=O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 1/20 0.49
PARP1 P09874 1/20 0.47
ALDH1A1 P00352 2/20 0.43
MAPK14 Q16539 2/20 0.42
SLC9A1 P19634 2/20 0.40
HPGD P15428 3/20 0.39
NPC1 O15118 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 2/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
BTK Q06187 1/20 0.38
MAPK1 P28482 1/20 0.38
MAP2K4 P45985 1/20 0.38
MAPKAPK2 P49137 1/20 0.38
MAPKAPK3 Q16644 1/20 0.38
MAPK6 Q16659 1/20 0.38
MAPKAPK5 Q8IW41 1/20 0.38
RAB9A P51151 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17907443 0.87 PARP1 (0.47) S1PR4PARP1ALDH1A1MAPK14SLC9A1
SCHEMBL17009620 0.80 BCAT2 (0.50) S1PR4PARP1ALDH1A1SLC9A1HPGD
SCHEMBL8108906 0.79 S1PR4 (0.50) S1PR4ALDH1A1HPGDSMN1; SMN2MEN1
SCHEMBL5679029 0.78 PARP1 (0.50) PARP1ALDH1A1HPGDNPC1SMN1; SMN2
SCHEMBL17907467 0.77 PARP1 (0.50) PARP1
SCHEMBL284479 0.77 MKNK1 (0.49) PARP1ALDH1A1HPGDNPC1SMN1; SMN2
SCHEMBL2128609 0.77 PARP1 (0.52) PARP1ALDH1A1SMN1; SMN2
SCHEMBL28244862 0.76 SLC22A12 (0.39) PARP1ALDH1A1MAPK14NPC1MAPT
SCHEMBL6825758 0.75 PARP1 (0.50) PARP1ALDH1A1SMN1; SMN2MAPTMAPK1
Hydrochloric Acid SCHEMBL27585323 0.75 MKNK1 (0.47) PARP1ALDH1A1HPGDNPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11254082-B2 Multi-layer tube UBE INDUSTRIES, LTD. (JP) 2022-02-22 US disclosed
US-10663092-B2 Multilayer tube UBE INDUSTRIES, LTD. (JP) 2020-05-26 US disclosed
EP-3042758-B1 LAMINATED TUBE UBE INDUSTRIES (JP) 2020-05-06 EP disclosed
EP-3461631-A1 MULTILAYER TUBE Ube Industries, Ltd. (JP) 2019-04-03 EP disclosed
EP-3192650-B1 LAYERED TUBE UBE INDUSTRIES (JP) 2019-01-23 EP disclosed
US-20170261133-A1 MULTILAYER TUBE UBE INDUSTRIES, LTD. (JP) 2017-09-14 US disclosed
EP-3192650-A1 LAYERED TUBE UBE Industries, Ltd. (JP) 2017-07-19 EP disclosed
US-20160214343-A1 MULTI-LAYER TUBE UBE INDUSTRIES, LTD. (JP) 2016-07-28 US disclosed
EP-3042758-A1 LAMINATED TUBE UBE Industries, Ltd. (JP) 2016-07-13 EP disclosed