SCHEMBL17918953

SCHEMBL17918953

O=C(O)C[C@H](NC(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SYNJ2 O15056 2/20 0.46
▸ GAA P10253 2/20 0.46
▸ KDM4E B2RXH2 1/20 0.46
▸ ABL1 P00519 1/20 0.46
▸ ALPL P05186 1/20 0.46
▸ POLB P06746 1/20 0.46
▸ ALPI P09923 1/20 0.46
▸ MAPT P10636 1/20 0.46
▸ ALPG P10696 1/20 0.46
▸ PABPC1 P11940 1/20 0.46
▸ RECQL P46063 1/20 0.46
▸ GALK1 P51570 1/20 0.46
▸ CASP7 P55210 1/20 0.46
▸ CASP6 P55212 1/20 0.46
▸ MCL1 Q07820 1/20 0.46
▸ RIN1 Q13671 1/20 0.46
▸ EIF4H Q15056 1/20 0.46
▸ KDR P35968 1/20 0.42
▸ LGALS8 O00214 1/20 0.42
▸ PYGB P11216 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17919001 0.86 SELP (0.48) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL17919043 0.84 ALDH1A1 (0.43) MAPTKDRLGALS8PYGB
SCHEMBL17918994 0.81 FOLH1 (0.43) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL17918895 0.80 SYNJ2 (0.52) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL17919002 0.80 PYGB (0.43) SYNJ2MAPTKDRLGALS8PYGB
SCHEMBL17918955 0.78 TYR (0.50) SYNJ2KDM4EMAPT
SCHEMBL8984078 0.78 SYNJ2 (0.57) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL28909065 0.77 SYNJ2 (0.48) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL17080337 0.77 SYNJ2 (0.48) SYNJ2GAAKDM4EABL1ALPL
SCHEMBL28463195 0.77 PYGB (0.50) GAAMAPTLGALS8PYGB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160200755-A1 GLYCOAMINO ACID AND USE THEREOF AJINOMOTO CO., INC. (JP) 2016-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160200755-A1 GLYCOAMINO ACID AND USE THEREOF GYPA, NGLY1, SLC6A15 SYNJ2 2299/4885GAA 88/4885KDM4E 4699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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