Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17921184 | 0.99 | ALDH1A1 (0.45) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL17921154 | 0.99 | DPP4 (0.46) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL17921147 | 0.95 | DPP4 (0.47) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL16512634 | 0.88 | HDAC1 (0.43) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL16511341 | 0.87 | HDAC1 (0.44) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL16511441 | 0.87 | HDAC1 (0.44) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL17921182 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAL3MBTL1NPC1RAB9A | |
| SCHEMBL16511764 | 0.83 | DPP4 (0.44) | DPP4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL17921183 | 0.83 | LMNA (0.35) | ALDH1A1KDM4ELMNAL3MBTL1POLB | |
| SCHEMBL17921155 | 0.82 | ALDH1A1 (0.34) | ALDH1A1KDM4ELMNAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | DUKE UNIVERSITY | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | Q6ZSR9, MRPL21, XDH | DPP4 2670/4885ALDH1A1 2944/4885KDM4E 4306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.