Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PRNP | P04156 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17921182 | 0.99 | ALDH1A1 (0.36) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL17921159 | 0.96 | RPS6KB2 (0.33) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL16511334 | 0.87 | MMP9 (0.36) | ALDH1A1RPS6KB2TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL17921161 | 0.86 | LMNA (0.33) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL16511435 | 0.86 | MMP9 (0.38) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL17921183 | 0.85 | LMNA (0.35) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL17921154 | 0.83 | DPP4 (0.46) | ALDH1A1LMNAHPGDL3MBTL1NPC1 | |
| SCHEMBL17921184 | 0.83 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDL3MBTL1NPC1 | |
| SCHEMBL17921168 | 0.83 | LTB4R (0.33) | ALDH1A1L3MBTL1PTGS1PTGS2NPC1 | |
| SCHEMBL16511778 | 0.83 | MMP9 (0.36) | ALDH1A1RPS6KB2TAS1R3TAS1R1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | DUKE UNIVERSITY | 2016-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200673-A1 | Antibacterial Compounds | Q6ZSR9, MRPL21, XDH | ALDH1A1 2944/4885LMNA 3247/4885PRNP 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.