SCHEMBL17930255

SCHEMBL17930255

C=c1c2ccc3c4cccc5cccc(c6ccc(c(=O)n1C(C)(C)C)c2c36)c54

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 2/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ HPGD P15428 2/20 0.33
▸ HSD17B10 Q99714 2/20 0.33
▸ MCL1 Q07820 1/20 0.33
▸ THRB P10828 1/20 0.33
▸ AHR P35869 2/20 0.33
▸ ERBB2 P04626 1/20 0.32
▸ FYN P06241 1/20 0.32
▸ MAOA P21397 1/20 0.32
▸ ACHE P22303 1/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ TDP1 Q9NUW8 2/20 0.31
▸ CYP3A4 P08684 1/20 0.30
▸ TSHR P16473 1/20 0.30
▸ L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14849938 0.79 KMT2A (0.38) CYP1A2ALDH1A1HPGDHSD17B10MCL1
SCHEMBL17930245 0.78 KMT2A (0.44) CYP1A2ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL14169090 0.73 KMT2A (0.41) CYP1A2ALDH1A1HPGDHSD17B10MCL1
SCHEMBL19455723 0.72 AHR (0.35) CYP1A2ALDH1A1HPGDHSD17B10MCL1
SCHEMBL12020634 0.72 MAPK1 (0.49) CYP1A2ALDH1A1HPGDHSD17B10THRB
SCHEMBL19370242 0.70 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10MEN1KMT2A
SCHEMBL29297667 0.69 FEN1 (0.41) CYP1A2ALDH1A1HPGDHSD17B10MCL1
SCHEMBL29354688 0.69 ALDH1A1 (0.63) CYP1A2ALDH1A1HPGDHSD17B10MCL1
SCHEMBL29369890 0.69 ALDH1A1 (0.63) CYP1A2ALDH1A1HPGDHSD17B10MCL1
SCHEMBL4848747 0.69 ALDH1A1 (0.63) CYP1A2ALDH1A1HPGDHSD17B10MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS SONY GROUP CORP (JP) 2024-06-27 — — US disclosed
US-12018159-B2 Ultra bright dimeric or polymeric dyes and methods for preparation of the same Sony Group Corporation (JP) 2024-06-25 — — US disclosed
US-11874280-B2 Use of divalent metals for enhancement of fluorescent signals Sony Group Corporation (JP) 2024-01-16 — — US disclosed
US-11827661-B2 Water soluble fluorescent or colored dyes comprising conjugating groups Sony Group Corporation (JP) 2023-11-28 — — US disclosed
US-11685835-B2 Ultra bright dimeric or polymeric dyes SONY CORPORATION (JP) 2023-06-27 — — US disclosed
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS Sony Group Corporation (JP) 2023-04-27 — — US disclosed
US-20180163052-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE Sony Group Corporation (JP) 2018-06-14 — — US disclosed
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2018-06-14 — — US disclosed
US-20180079909-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES SONY CORPORATION (JP) 2018-03-22 — — US disclosed
US-20180065998-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS Sony Group Corporation (JP) 2018-03-08 — — US disclosed
US-9851359-B2 Ultra bright dimeric or polymeric dyes with spacing linker groups SONY CORPORATION OF AMERICA (US) 2017-12-26 — — US disclosed
US-20170292957-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS SONY CORPORATION (JP) 2017-10-12 — — US disclosed
US-9765220-B2 Water soluble fluorescent or colored dyes and methods for their use SONY CORPORATION (JP) 2017-09-19 — — US disclosed
US-20160208100-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE Sony Group Corporation (JP) 2016-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180163052-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE CHRM1, CHRM2, IK CYP1A2 1000/4885ALDH1A1 357/4885HPGD 2913/4885
US-20180164322-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 CYP1A2 4675/4885ALDH1A1 1336/4885HPGD 4169/4885
US-20160208100-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES AND METHODS FOR THEIR USE CHRM1, CHRM2, IK CYP1A2 1000/4885ALDH1A1 357/4885HPGD 2913/4885
US-20180065998-A1 WATER SOLUBLE FLUORESCENT OR COLORED DYES COMPRISING CONJUGATING GROUPS CHRM1, CHRM2, H1-0 CYP1A2 2746/4885ALDH1A1 965/4885HPGD 3364/4885
US-20240207423-A1 PROGAMMABLE POLYMERIC DRUGS OPRM1, CHRM1, TUBB3 CYP1A2 1729/4885ALDH1A1 2019/4885HPGD 3392/4885
US-11827661-B2 Water soluble fluorescent or colored dyes comprising conjugating groups CHRM1, CHRM2, H1-0 CYP1A2 2746/4885ALDH1A1 965/4885HPGD 3364/4885
US-20230129481-A1 ULTRA BRIGHT DIMERIC OR POLYMERIC DYES WITH SPACING LINKER GROUPS IK, MTCL3, RRM1 CYP1A2 4675/4885ALDH1A1 1336/4885HPGD 4169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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