SCHEMBL14169090

SCHEMBL14169090

C=c1c2cccc3cccc(c(=O)n1C)c32

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 4/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ KDM4E B2RXH2 6/20 0.40
▸ ALDH1A1 P00352 6/20 0.39
▸ HSD17B10 Q99714 4/20 0.39
▸ MAPT P10636 3/20 0.39
▸ HTT P42858 1/20 0.39
▸ ADORA3 P0DMS8 1/20 0.38
▸ ADORA2A P29274 1/20 0.38
▸ ADORA2B P29275 1/20 0.38
▸ ADORA1 P30542 1/20 0.38
▸ AHR P35869 1/20 0.37
▸ GAA P10253 2/20 0.37
▸ PKM P14618 1/20 0.37
▸ CASP1 P29466 1/20 0.37
▸ GALK1 P51570 1/20 0.37
▸ BLM P54132 1/20 0.37
▸ CASP7 P55210 1/20 0.37
▸ SAE1 Q9UBE0 1/20 0.37
▸ UBA2 Q9UBT2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14849938 0.95 KMT2A (0.38) KMT2AMEN1KDM4EALDH1A1HSD17B10
SCHEMBL20664933 0.81 ALDH1A1 (0.46) KMT2AMEN1KDM4EALDH1A1HSD17B10
SCHEMBL23396287 0.79 CYP1B1 (0.42) KMT2AMEN1KDM4EALDH1A1MAPT
SCHEMBL13716839 0.78 MAPT (0.42) KMT2AMEN1KDM4EALDH1A1HSD17B10
SCHEMBL15267178 0.78 ADORA3 (0.33) KDM4EALDH1A1HSD17B10MAPTHTT
SCHEMBL29297667 0.77 FEN1 (0.41) KMT2AMEN1KDM4EALDH1A1HSD17B10
SCHEMBL12355076 0.76 ADORA3 (0.33) KDM4EADORA3ADORA2AADORA2BADORA1
SCHEMBL22182105 0.75 TDP1 (0.57) KDM4EALDH1A1MAPTHPGDNPC1
SCHEMBL17930255 0.73 CYP1A2 (0.33) KMT2AMEN1ALDH1A1HSD17B10AHR
SCHEMBL17281122 0.70 ALDH1A1 (0.46) ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11649254-B2 Compound, a display panel and an electronic device Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) 2023-05-16 — — US disclosed
WO-2018106200-A1 ORIGINAL DRUG MOLECULES FOR THE TREATMENT OF PARASITIC AND NEOPLASTIC DISEASES AND METHODS FOR PREPARATION THEREOF T.C MEDİPOL ÜNİVERSİTESİ (TR) 2018-06-14 — — WO disclosed
US-20160340387-A1 NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE ALPHABETA AB (SE) 2016-11-24 — — US disclosed
US-9399730-B2 Wavelength conversion material as encapsulate for solar module systems to enhance solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-26 — — US disclosed
US-9394479-B2 Wavelength conversion film having pressure sensitive adhesive layer to enhance solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-19 — — US disclosed
US-9382424-B2 Highly-fluorescent and photo-stable chromophores for enhanced solar harvesting efficiency NITTO DENKO CORPORATION (JP) 2016-07-05 — — US disclosed
US-20160108310-A1 WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES NITTO DENKO CORPORATION (JP) 2016-04-21 — — US disclosed
US-20150041052-A1 WAVELENGTH CONVERSION LAYER ON A GLASS PLATE TO ENHANCE SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2015-02-12 — — US disclosed
US-20150041042-A1 PRESSURE SENSITIVE ADHESIVE TYPE OF WAVELENGTH CONVERSION TAPE FOR ENHANCING SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2015-02-12 — — US disclosed
US-20140311566-A1 MICROSTRUCTURED WAVELENGTH CONVERSION FILMS FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2014-10-23 — — US disclosed
US-20130139868-A1 WAVELENGTH CONVERSION MATERIAL AS ENCAPSULATE FOR SOLAR MODULE SYSTEMS TO ENHANCE SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-06-06 — — US disclosed
US-20130089946-A1 WAVELENGTH CONVERSION FILM HAVING PRESSURE SENSITIVE ADHESIVE LAYER TO ENHANCE SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-04-11 — — US disclosed
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY NITTO DENKO CORPORATION (JP) 2013-03-28 — — US disclosed
US-7385064-B1 Catalysts for use in enantioselective synthesis THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 2008-06-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340387-A1 NOVEL LIGANDS FOR PREVENTION OF NEUROTOXICITY OF THE ALZHEIMER'S DISEASE RELATED AMYLOID-BETA PEPTIDE APP, BACE1, PSEN1 KMT2A 4629/4885MEN1 3447/4885KDM4E 4836/4885
US-20130074927-A1 HIGHLY-FLUORESCENT AND PHOTO-STABLE CHROMOPHORES FOR ENHANCED SOLAR HARVESTING EFFICIENCY SUN2, NES, CRY1 KMT2A 645/4885MEN1 970/4885KDM4E 983/4885
US-11649254-B2 Compound, a display panel and an electronic device TEAD2, OCIAD2, TEAD4 KMT2A 3001/4885MEN1 4643/4885KDM4E 3038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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