Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17933354 | 0.61 | ALDH1A1 (0.33) | TAAR1ALDH1A1FDPSTDP1SLC6A2 | |
| SCHEMBL17933366 | 0.59 | FDPS (0.35) | TAAR1ALDH1A1FDPSTDP1SLC6A2 | |
| SCHEMBL17933360 | 0.59 | ALDH1A1 (0.32) | TAAR1ALDH1A1FDPSTDP1SLC6A2 | |
| SCHEMBL17933349 | 0.59 | SCN10A (0.39) | TAAR1ALDH1A1FDPSTDP1SLC6A2 | |
| SCHEMBL17933370 | 0.58 | FDPS (0.38) | TAAR1ALDH1A1FDPSSLC6A2 | |
| SCHEMBL17933358 | 0.58 | ALDH1A1 (0.31) | TAAR1ALDH1A1FDPSTDP1SLC6A2 | |
| SCHEMBL17933355 | 0.58 | FBP1 (0.38) | — | |
| Amphetamine SCHEMBL113682 | 0.57 | TAAR1 (0.76) | TAAR1SLC6A2 | |
| Dextroamphetamine SCHEMBL547496 | 0.57 | TAAR1 (0.76) | TAAR1SLC6A2 | |
| Dextroamphetamine SCHEMBL17924971 | 0.56 | TAAR1 (0.73) | TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | UNIVERSITY OF SHEFFIELD (GB) | 2016-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207948-A1 | PHOSPHOHISTIDINE AND PHOSPHOTYROSINE ANALOGUES | HRH3, CYTH3, CYTH2 | TAAR1 4570/4885ALDH1A1 4655/4885FDPS 3192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.