Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 7/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.36 |
| ▸ | CBR1 | P16152 | 2/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17942946 | 0.87 | ALDH1A1 (0.36) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL17942945 | 0.85 | ALDH1A1 (0.35) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL19465282 | 0.83 | MAOA (0.36) | MAOBMAOA | |
| SCHEMBL17942940 | 0.83 | AKR1B10 (0.43) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL762318 | 0.82 | AKR1B10 (0.43) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL25168020 | 0.80 | AKR1B10 (0.43) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL30422928 | 0.80 | AKR1B10 (0.43) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL25167999 | 0.80 | AKR1B10 (0.43) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL30423318 | 0.80 | AKR1B10 (0.43) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 | |
| SCHEMBL25167167 | 0.80 | NAAA (0.44) | MAOBMAOAAKR1B10AKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11175204-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2021-11-16 | — | — | US | disclosed |
| US-9400273-B1 | 7-hydroxycoumarin-based cell-tracking reagents | Life Technologies Corporation (US) | 2016-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11175204-B1 | 7-hydroxycoumarin-based cell-tracking reagents | MKI67, DCX, CDK7 | MAOB 2476/4885MAOA 3288/4885AKR1B10 3285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.