SCHEMBL17943377

SCHEMBL17943377

c1ccc(-c2nc(-c3ccc(-c4ccc(-n5c6ccccc6c6ccc7ccccc7c65)cc4)cc3)nc(-c3ccc4c5ccccc5c5ccccc5c4c3)n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ L3MBTL1 Q9Y468 1/20 0.37
▸ PDPK1 O15530 4/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ CYP1A1 P04798 1/20 0.34
▸ CYP1B1 Q16678 1/20 0.34
▸ MAPT P10636 3/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ RECQL P46063 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HDAC4 P56524 1/20 0.33
▸ RXRA P19793 1/20 0.33
▸ MEN1 O00255 3/20 0.33
▸ KMT2A Q03164 3/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26007467 0.95 KDM4E (0.37) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL25140465 0.94 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL21524323 0.94 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL17943425 0.94 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL17943440 0.94 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL17943405 0.94 L3MBTL1 (0.42) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL24361936 0.93 KDM4E (0.38) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL24361941 0.93 KDM4E (0.37) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL24361924 0.93 KDM4E (0.38) ATMKDM4EL3MBTL1PDPK1CYP1A2
SCHEMBL24154541 0.93 KDM4E (0.37) ATMKDM4EL3MBTL1PDPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer LG CHEM, LTD. (KR) 2023-08-22 — — US disclosed
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2020-09-17 — — US disclosed
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer LG CHEM, LTD. (KR) 2020-07-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-9595679-B2 Organic light emitting diode LG CHEM, LTD. (KR) 2017-03-14 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE LG CHEM, LTD. (KR) 2016-09-22 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160225993-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-08-04 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed
US-20160218288-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2016-07-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200295264-A1 ORGANIC LIGHT EMITTING DEVICE TPH1, DRD1, CYP1A1 ATM 2503/4885KDM4E 2126/4885L3MBTL1 2025/4885
US-10714692-B2 Organic light emitting device having a carbazole-based compound formed between cathode and light emitting layer and a spirobifluorene-monoamine based compound formed between anode and light emitting layer COMT, MAOB, MAOA ATM 641/4885KDM4E 2523/4885L3MBTL1 1067/4885
US-20160276594-A1 ORGANIC LIGHT EMITTING DIODE CRY1, CRY2, NR2E3 ATM 1728/4885KDM4E 2742/4885L3MBTL1 12/4885
US-11737354-B2 Organic light emitting device having a carbazole-based compound formed between a cathode and a light emitting layer and a spirobifluorene-monoamine-based compound formed between an anode and a light emitting layer DRD1, TPH1, DRD3 ATM 1444/4885KDM4E 2285/4885L3MBTL1 1918/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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