Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | PYGB | P11216 | 1/20 | 0.33 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17945414 | 0.83 | AMY1A (0.32) | AMY1APYGBLGALS8FBP1 | |
| SCHEMBL1104569 | 0.82 | SMPD1 (0.45) | — | |
| SCHEMBL17945756 | 0.81 | AMY1A (0.33) | AMY1A | |
| SCHEMBL9912325 | 0.76 | AMY2A (0.39) | AMY1APYGBLGALS8 | |
| SCHEMBL11892843 | 0.76 | AMY2A (0.39) | AMY1APYGBLGALS8 | |
| SCHEMBL1104571 | 0.75 | AMY1A (0.41) | AMY1AFBP1 | |
| SCHEMBL13205044 | 0.74 | AMY1A (0.38) | AMY1APYGBLGALS8 | |
| SCHEMBL10188789 | 0.74 | FBP1 (0.49) | FBP1 | |
| SCHEMBL23603150 | 0.72 | LGALS8 (0.45) | AMY1APYGBLGALS8 | |
| SCHEMBL21077738 | 0.72 | LGALS8 (0.45) | AMY1APYGBLGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160215275-A1 | Chemically Ligated RNAs for CRISPR/Cas9-lgRNA Complexes as Antiviral Therapeutic Agents | ZHONG MINGHONG (US) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215275-A1 | Chemically Ligated RNAs for CRISPR/Cas9-lgRNA Complexes as Antiviral Therapeutic Agents | SRRT, TRDMT1, ZFR | AMY1A 4572/4885PYGB 3432/4885LGALS8 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.