Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 3/20 | 0.66 |
| ▸ | GALNT2 | Q10471 | 2/20 | 0.66 |
| ▸ | GALNT1 | Q10472 | 1/20 | 0.66 |
| ▸ | GALNT3 | Q14435 | 1/20 | 0.66 |
| ▸ | GALNT10 | Q86SR1 | 1/20 | 0.66 |
| ▸ | GALNT13 | Q8IUC8 | 1/20 | 0.66 |
| ▸ | GALNT6 | Q8NCL4 | 1/20 | 0.66 |
| ▸ | GALNT14 | Q96FL9 | 1/20 | 0.66 |
| ▸ | ESR2 | Q92731 | 15/20 | 0.48 |
| ▸ | ESR1 | P03372 | 12/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PLK4 | O00444 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GSR | P00390 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370098 | 0.80 | PKLR (1.00) | PKLRGALNT2GALNT1GALNT3GALNT10 | |
| SCHEMBL7980209 | 0.80 | PKLR (1.00) | PKLRGALNT2GALNT1GALNT3GALNT10 | |
| SCHEMBL22619263 | 0.75 | ESR2 (0.43) | PKLRGALNT2GALNT1GALNT3GALNT10 | |
| SCHEMBL8188021 | 0.72 | PTGS2 (0.51) | ESR2KDM4EMEN1CA12CA1 | |
| SCHEMBL10561648 | 0.72 | MAOB (0.65) | KDM4ELMNATP53GAAMAPT | |
| SCHEMBL22431062 | 0.70 | ESR2 (0.76) | PKLRGALNT2GALNT1GALNT3GALNT10 | |
| SCHEMBL26768213 | 0.70 | PKLR (0.79) | PKLRGALNT2GALNT1GALNT3GALNT10 | |
| SCHEMBL2922254 | 0.68 | HSP90AA1 (0.50) | KDM4EMEN1AURKAUSP2LMNA | |
| SCHEMBL29369342 | 0.66 | PKLR (1.00) | PKLRGALNT2GALNT1GALNT3GALNT10 | |
| SCHEMBL15423100 | 0.66 | PKLR (1.00) | PKLRGALNT2GALNT1GALNT3GALNT10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160213643-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | AMAZENTIS SA (CH) | 2016-07-28 | — | — | US | disclosed |
| US-20160213641-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160213643-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | NLN, TUFM, TFAM | PKLR 1697/4885GALNT2 738/4885GALNT1 627/4885 |
| US-20160213641-A1 | Compositions and Methods for Improving Mitochondrial Function and Treating Neurodegenerative Diseases and Cognitive Disorders | NLN, TUFM, TFAM | PKLR 1697/4885GALNT2 738/4885GALNT1 627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.