Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | QDPR | P09417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17950674 | 0.73 | GPR139 (0.46) | — | |
| SCHEMBL17950446 | 0.72 | GPR139 (0.44) | — | |
| SCHEMBL21240512 | 0.72 | SLC9A1 (0.47) | BACE1CHRM4QDPR | |
| SCHEMBL3259871 | 0.72 | PARP1 (0.40) | — | |
| SCHEMBL17950592 | 0.71 | PRMT5 (0.53) | PRMT5WDR77BACE1EGLN1GAA | |
| SCHEMBL17950599 | 0.70 | GPR139 (0.46) | HDAC4HDAC2HDAC8 | |
| SCHEMBL25151685 | 0.69 | ACVR1 (0.58) | BACE1GAA | |
| SCHEMBL17950554 | 0.69 | CASP3 (0.45) | — | |
| SCHEMBL17950584 | 0.69 | GPR139 (0.47) | — | |
| SCHEMBL38660888 | 0.68 | GPR3 (0.47) | PRMT5WDR77BACE1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016116058-A1 | TRIAZINE HETEROCYCLIC COMPOUND WITH NEMATICIDAL ACTIVITY AND PREPARATION METHOD THEREFOR AND USAGE THEREOF | 华东理工大学 | 2016-07-28 | — | — | WO | disclosed |