Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20786946 | 0.82 | LMNA (0.48) | MAPK1TNFLMNAMEN1KMT2A | |
| SCHEMBL6920364 | 0.82 | LMNA (0.49) | MAPK1TNFLMNAMEN1KMT2A | |
| SCHEMBL4539817 | 0.81 | HTR1A (0.50) | MAPK1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL29025444 | 0.78 | LMNA (0.46) | MAPK1TNFLMNAMEN1KMT2A | |
| SCHEMBL6921490 | 0.78 | LMNA (0.54) | MAPK1TNFLMNAMEN1KMT2A | |
| SCHEMBL20809184 | 0.78 | LMNA (0.46) | MAPK1TNFLMNAMEN1KMT2A | |
| SCHEMBL20786926 | 0.78 | MAPT (0.46) | MAPK1TNFLMNAMEN1KMT2A | |
| SCHEMBL20786939 | 0.77 | RAB9A (0.54) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL1500289 | 0.76 | L3MBTL1 (0.48) | MAPK1LMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL28488309 | 0.76 | KMT2A (0.45) | MEN1KMT2AHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016116058-A1 | TRIAZINE HETEROCYCLIC COMPOUND WITH NEMATICIDAL ACTIVITY AND PREPARATION METHOD THEREFOR AND USAGE THEREOF | 华东理工大学 | 2016-07-28 | — | — | WO | disclosed |