Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 11/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | STK17B | O94768 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952929 | 0.90 | MAOA (0.42) | P2RX4MAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL22068587 | 0.86 | NISCH (0.36) | MAOAMAOBNPSR1HTT | |
| SCHEMBL17952722 | 0.86 | P2RX4 (0.37) | P2RX4MAOAMAOBMAPTSMN1; SMN2 | |
| SCHEMBL21396792 | 0.84 | CYP11B2 (0.37) | CYP17A1 | |
| SCHEMBL21927334 | 0.81 | ATR (0.36) | MAOAMAOBCYP1A2HTT | |
| SCHEMBL29534495 | 0.81 | MGLL (0.40) | P2RX4MAPTSMN1; SMN2NPSR1CDK8 | |
| SCHEMBL21922119 | 0.80 | NPC1 (0.43) | MAPTSMN1; SMN2CYP1A2NPC1RAB9A | |
| SCHEMBL21927305 | 0.80 | ATR (0.35) | CYP1A2HTT | |
| SCHEMBL17952784 | 0.79 | RPS6KA3 (0.41) | P2RX4MAOAMAOBSMN1; SMN2CDK8 | |
| SCHEMBL17952925 | 0.78 | RPS6KA3 (0.40) | P2RX4MAOAMAOBSMN1; SMN2CDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10544361-B2 | Pyridines and derivatives thereof as components for use in optoelectronic components | CYNORA GMBH (DE) | 2020-01-28 | — | — | US | disclosed |