Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17952984 | 0.94 | CHRM2 (0.34) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17169024 | 0.88 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10SRD5A1ALDH1A1HPGD | |
| SCHEMBL17952985 | 0.86 | DRD2 (0.34) | SMN1; SMN2HTR7HTR1AHSD17B10SRD5A1 | |
| SCHEMBL19336713 | 0.86 | SMN1; SMN2 (0.34) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17082307 | 0.85 | HTR7 (0.34) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17952987 | 0.84 | JAK2 (0.38) | SMN1; SMN2SRD5A1ALDH1A1HPGDROCK1 | |
| SCHEMBL17074017 | 0.84 | SMN1; SMN2 (0.32) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17952994 | 0.83 | HTR7 (0.33) | HTR7HTR1ASLC6A4CYP2D6SLC6A2 | |
| SCHEMBL7039658 | 0.82 | ALDH1A1 (0.36) | HTR7HTR1ASLC6A4CYP2D6SLC6A2 | |
| SCHEMBL17169025 | 0.81 | MEN1 (0.38) | SMN1; SMN2SRD5A1ALDH1A1HPGDROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9790240-B2 | Ligand compound, a preparation method thereof, a transition metal compound, and a preparation method thereof | LG CHEM, LTD. (KR) | 2017-10-17 | — | — | US | disclosed |
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | LG CHEM, LTD. (KR) | 2016-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215004-A1 | A NOVEL LIGAND COMPOUND, A PREPARATION METHOD THEREOF, A TRANSITION METAL COMPOUND, AND A PREPARATION METHOD THEREOF | CD40LG, OSTC, TNFSF10 | SMN1; SMN2 4715/4885HDAC3 4183/4885HDAC1 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.