⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4199276 | 0.83 | LMNA (0.46) | — | |
| SCHEMBL133775 | 0.78 | — | — | |
| SCHEMBL4209196 | 0.78 | LMNA (0.36) | — | |
| SCHEMBL5790232 | 0.78 | ALDH1A1 (0.36) | — | |
| SCHEMBL337639 | 0.76 | — | — | |
| SCHEMBL4201284 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL4205138 | 0.76 | ALDH1A1 (0.39) | — | |
| SCHEMBL133787 | 0.76 | — | — | |
| SCHEMBL25800877 | 0.76 | — | — | |
| SCHEMBL20819674 | 0.75 | PRMT3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3085388-A1 | HYPERBRANCHED POLYMER CONJUGATES VIA NON-ENZYMATIC CLEAVABLE LINKER | Ascendis Pharma Growth Disorders Division A/S (DK) | 2016-10-26 | — | — | EP | disclosed |
| EP-2090323-B1 | Hyperbranched polymer conjugates via non-enzymatic cleavable linker | ASCENDIS PHARMA GROWTH DISORDERS DIVISION AS (DK) | 2016-07-27 | — | — | EP | disclosed |