Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 11/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19367152 | 0.83 | HTR6 (0.41) | HTR6HTTTSHRALDH1A1KDM4E | |
| SCHEMBL20252206 | 0.82 | HTR6 (0.35) | HTR6HTTALDH1A1KDM4EMAPT | |
| SCHEMBL17954485 | 0.81 | HTR6 (0.40) | HTR6HTTTSHRALDH1A1KDM4E | |
| SCHEMBL19367109 | 0.77 | LMNA (0.39) | HTR6HTTTSHRALDH1A1KDM4E | |
| SCHEMBL22523899 | 0.75 | HTR6 (0.44) | HTR6HTTTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL20444739 | 0.73 | MAPT (0.40) | HTTALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL19846037 | 0.73 | FEN1 (0.38) | HTR6HTTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17954479 | 0.72 | MAPT (0.37) | HTTALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL19367122 | 0.72 | PGR (0.38) | HTTTSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL18194398 | 0.71 | ALDH1A1 (0.39) | HTR6HTTTSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247768-B1 | NAPHTHYL SUBSTITUTED ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2019-03-13 | — | — | EP | disclosed |
| WO-2016116510-A1 | NAPTHYL-SUBSTITUTED ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC COMPONENTS | CYNORA GMBH (DE) | 2016-07-28 | — | — | WO | disclosed |