Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14707139 | 0.93 | SLC6A9 (0.41) | S1PR1SLC6A9S1PR3DPP4DPP7 | |
| SCHEMBL14695466 | 0.88 | GPR119 (0.53) | DPP4DPP7GPR119 | |
| SCHEMBL19413494 | 0.86 | GPR119 (0.44) | S1PR1S1PR3MAPTHTTGPR119 | |
| SCHEMBL14695105 | 0.84 | DRD2 (0.54) | S1PR1S1PR3HDAC6LMNASMN1; SMN2 | |
| SCHEMBL17965205 | 0.83 | GPR119 (0.46) | S1PR1SLC6A9S1PR3DPP4DPP7 | |
| SCHEMBL17965092 | 0.79 | HDAC6 (0.41) | S1PR1SLC6A9S1PR3DPP4DPP7 | |
| SCHEMBL17965087 | 0.78 | GPR119 (0.46) | S1PR1SLC6A9S1PR3DPP4DPP7 | |
| SCHEMBL14695802 | 0.77 | GPR119 (0.54) | GPR119 | |
| SCHEMBL14707125 | 0.76 | GPR119 (0.46) | S1PR1SLC6A9S1PR3DPP4DPP7 | |
| SCHEMBL14695589 | 0.75 | PTGS2 (0.45) | HDAC6MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718279-B1 | NOVEL COMPOUNDS AS MODULATORS OF GPR-119 | RHIZEN PHARMACEUTICALS SA (CH) | 2016-08-10 | — | — | EP | claimed |