SCHEMBL1797463

SCHEMBL1797463

NC(N)=NC1CCCCC1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 8/20 0.54
KDM4E B2RXH2 1/20 0.44
EPHX1 P07099 2/20 0.39
HIF1A Q16665 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
ALDH1A1 P00352 2/20 0.36
ALOX15 P16050 1/20 0.35
NOS2 P35228 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25333580 1.00 SIGMAR1 (0.54) SIGMAR1KDM4EEPHX1HIF1AGRIN2D
SCHEMBL23736060 1.00 SIGMAR1 (0.54) SIGMAR1KDM4EEPHX1HIF1AGRIN2D
Hydrochloric Acid SCHEMBL16702639 0.97 SIGMAR1 (0.52) SIGMAR1KDM4EEPHX1HIF1AGRIN2D
SCHEMBL1794834 0.97
Hydrochloric Acid SCHEMBL1009224 0.94 SIGMAR1 (0.48) SIGMAR1KDM4EEPHX1HIF1AGRIN2D
Sulfuric Acid SCHEMBL11565002 0.88 SIGMAR1 (0.45) SIGMAR1KDM4EEPHX1HIF1AGRIN2D
Sulfuric Acid SCHEMBL11557898 0.88 SIGMAR1 (0.45) SIGMAR1KDM4EEPHX1HIF1AGRIN2D
Sulfuric Acid SCHEMBL11559298 0.85 KDM4E (0.43) SIGMAR1KDM4EEPHX1GRIN2DGRIN3B
SCHEMBL1797777 0.84
SCHEMBL19038544 0.79 SIGMAR1 (0.47) SIGMAR1KDM4EEPHX1HIF1AGRIN2D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115025643-B Functionalized polyvinylidene fluoride ultrafiltration membrane and preparation method and application thereof 北京师范大学 2023-07-18 CN claimed
CN-115341296-A Wear-resistant fiber for clothing and preparation method of fabric of wear-resistant fiber 创姿服饰(上海)有限公司 2022-11-15 CN claimed
WO-2020218835-A1 NOVEL POLYIMIDE-TYPE POLYMER AND PREPARATION METHOD THEREFOR 서울대학교 산학협력단 2020-10-29 WO claimed
CN-101684083-B Guanidyl alkanoylamino substituted tetracycline derivative SHANDONG XUANZHU MEDICINE TECHNOLOGY CO LTD 2011-10-05 CN claimed
CN-101759604-A Guanidyl substitutional tetracycline derivative SHANDONG XUANZHU PHARM TECH CO 2010-06-30 CN claimed
CN-101684083-A Guanidyl alkanoylamino substituted tetracycline derivative SHANDONG XUANZHU MEDICINE TECH 2010-03-31 CN claimed
US-20090194124-A1 Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine MALLE GERARD 2009-08-06 US claimed
US-20090139537-A1 HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE L'OREAL S.A. 2009-06-04 US claimed
US-20050136017-A1 Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin L'OREAL S.A. (FR) 2005-06-23 US claimed
US-20050129645-A1 Hair shaping composition comprising at least one non-hydroxide imine L'OREAL 2005-06-16 US claimed
EP-1532963-A1 Composition for straightening the hair comprising at least one imine not being an hydroxide L'OREAL (FR) 2005-05-25 EP claimed
EP-1532960-A1 Hair styling composition containing a non-hydroxide imine L'OREAL (FR) 2005-05-25 EP claimed
US-20260109849-A1 EPOXY RESIN COMPOSITION, RESIN PASTE, FILM-TYPE ADHESIVE, PRINTED WIRING BOARD, SEMICONDUCTOR CHIP PACKAGE, AND ELECTRONIC DEVICE ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-04-23 US disclosed
US-12410164-B2 Heterocyclic compounds and medical use thereof FONDAZIONE TELETHON (IT) 2025-09-09 US disclosed
WO-2025121026-A1 EPOXY RESIN COMPOSITION, RESIN PASTE, RESIN FILM, AND SEMICONDUCTOR DEVICE 旭化成株式会社 2025-06-12 WO disclosed
CN-119894957-A Epoxy resin composition, resin paste, film-type adhesive, printed circuit board, semiconductor chip package, and electronic device 旭化成株式会社 2025-04-25 CN disclosed
US-4619888-A HIGH DENSITY IMAGES; IMPROVED SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1986-10-28 US disclosed
EP-0088180-A1 N-phosphonomethylglycine derivatives Geshuri Laboratories Ltd. (IL) 1983-09-14 EP disclosed
US-4397676-A HERBICIDES GESHURI LABORATORIES LTD. (IL) 1983-08-09 US disclosed
US-4347310-A INCREASED PHOTOSENZITIVITY USING GUANIDINE DERIVTIVES AS SENSITIZERS; PHOTOSTABILITY; STORAGE STABILITY ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1982-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090139537-A1 HAIR RELAXING COMPOSITION COMPRISING AT LEAST ONE NON-HYDROXIDE IMINE KRT18, INMT, INHA SIGMAR1 1743/4885KDM4E 308/4885EPHX1 3319/4885
US-20090194124-A1 Hair Shaping Kit and Process Comprising at Least One Non-Hydroxide Imine KRT18, KIT, PRDM7 SIGMAR1 3735/4885KDM4E 251/4885EPHX1 2311/4885
US-20050129645-A1 Hair shaping composition comprising at least one non-hydroxide imine KRT18, INHA, H1-5 SIGMAR1 2720/4885KDM4E 419/4885EPHX1 2359/4885
US-20260109849-A1 EPOXY RESIN COMPOSITION, RESIN PASTE, FILM-TYPE ADHESIVE, PRINTED WIRING BOARD, SEMICONDUCTOR CHIP PACKAGE, AND ELECTRONIC DEVICE ASH2L, DOT1L, ASH1L SIGMAR1 1327/4885KDM4E 160/4885EPHX1 163/4885
US-12410164-B2 Heterocyclic compounds and medical use thereof NPPA, NPR1, CYC1 SIGMAR1 1083/4885KDM4E 4181/4885EPHX1 1991/4885
US-20050136017-A1 Cosmetic containing an imine reactive with the cystines of keratin fibers via a beta-elimination reaction to produce dehydroalanine and lead to formation of lanthionine in a medium free of polyhydroxylated alkane; guanidine and/or amidine imines such as dimethylguanidine; noncaustic for use on hair, skin BHMT, KRT18, INMT SIGMAR1 1048/4885KDM4E 1258/4885EPHX1 3675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.