Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16586347 | 0.81 | LMNA (0.48) | CYP1A2CYP3A4CYP2D6L3MBTL1KMT2A | |
| SCHEMBL17975237 | 0.79 | CYP1A2 (0.51) | CYP1A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL17975232 | 0.78 | KMT2A (0.48) | CYP1A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL17975235 | 0.78 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL30306278 | 0.78 | CNR2 (0.62) | CYP1A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL822015 | 0.75 | ALDH1A1 (0.68) | CYP1A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL17960688 | 0.75 | SMN1; SMN2 (0.53) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL9486088 | 0.73 | NPC1 (0.51) | CYP1A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL21809122 | 0.73 | CYP2C9 (0.52) | CYP1A2CYP3A4CYP2D6NPC1RAB9A | |
| SCHEMBL17975238 | 0.73 | SMN1; SMN2 (0.47) | CYP1A2CYP3A4CYP2D6NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2016-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222042-A1 | NOVEL PHOSPHINES, SYNTHESIS THEREOF AND THEIR USE IN CATALYSIS | PHOSPHO1, PPIP5K2, PDXK | CYP1A2 3343/4885CYP3A4 1558/4885CYP2D6 3328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.