SCHEMBL822015

SCHEMBL822015

CC(=O)n1c(C)nc2ccccc21

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.68
KMT2A Q03164 1/20 0.68
HTT P42858 2/20 0.55
NPC1 O15118 2/20 0.53
RAB9A P51151 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
ASAH1 Q13510 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
POLB P06746 1/20 0.50
ALDH3A1 P30838 2/20 0.49
KDM4E B2RXH2 1/20 0.49
PKM P14618 1/20 0.49
APAF1 O14727 1/20 0.49
MAPK1 P28482 1/20 0.49
HPGD P15428 1/20 0.48
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27945131 0.85 KMT2A (0.68) ALDH1A1KMT2AHTTNPC1RAB9A
SCHEMBL22540485 0.84 KMT2A (0.66) ALDH1A1KMT2AHTTNPC1RAB9A
SCHEMBL19365059 0.81 ALDH1A1 (0.58) ALDH1A1KMT2AHTTNPC1RAB9A
SCHEMBL28820818 0.81 ALDH1A1 (0.58) ALDH1A1KMT2AHTTNPC1RAB9A
SCHEMBL29145178 0.81 L3MBTL1 (0.66) ALDH1A1KMT2AHTTNPC1RAB9A
SCHEMBL9486088 0.80 NPC1 (0.51) ALDH1A1KMT2ANPC1RAB9AL3MBTL1
SCHEMBL18068779 0.79 ALDH1A1 (0.44) ALDH1A1KMT2AHTTNPC1RAB9A
SCHEMBL10259406 0.79 KMT2A (0.44) ALDH1A1KMT2ANPC1RAB9APOLB
SCHEMBL10259403 0.79 RAB9A (0.44) ALDH1A1KMT2AHTTNPC1RAB9A
Hydrochloric Acid SCHEMBL7177614 0.78 ALDH1A1 (0.48) ALDH1A1KMT2AHTTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11287756-B2 Positive charging electrophotographic photoreceptor, electrophotographic cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-29 US disclosed
US-20210220251-A1 HAIR COLORING COMPOSITION AND METHODS FOR ITS APPLICATION AND REMOVAL HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) 2021-07-22 US disclosed
US-10815222-B2 Compounds for use in the treatment of kinetoplastid infection C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) 2020-10-27 US disclosed
US-20200095232-A1 COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) 2020-03-26 US disclosed
WO-2020008074-A1 HAIR COLORING COMPOSITION AND METHODS FOR ITS APPLICATION AND REMOVAL HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) 2020-01-09 WO disclosed
US-20160111698-A1 SEPARATOR FOR LITHIUM SECONDARY BATTERY AND METHOD FOR MANUFACTURING SAME IUCF HYU (KR) 2016-04-21 US disclosed
US-8906586-B2 Coating fluid for photosensitive-layer formation, process for producing the same, photoreceptor produced with the coating fluid, image-forming apparatus employing the photoreceptor, and electrophotographic cartridge employing the photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-09 US disclosed
US-8906586-B2 Coating fluid for photosensitive-layer formation, process for producing the same, photoreceptor produced with the coating fluid, image-forming apparatus employing the photoreceptor, and electrophotographic cartridge employing the photoreceptor MITSUBISHI CHEMICAL CORPORATION (JP) 2014-12-09 US disclosed
EP-2196859-B1 Coating fluid for forming undercoat layer and electrographic photoreceptor having undercoat layer formed by applying said coating fluid MITSUBISHI CHEM CORP (JP) 2014-01-22 EP disclosed
US-20130280438-A1 METHOD FOR PRODUCING POLARIZING FILM, AND LIQUID CRYSTAL DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2013-10-24 US disclosed
US-20090027597-A1 METHOD FOR PRODUCING POLARIZING FILM, AND LIQUID CRYSTAL DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2009-01-29 US disclosed
EP-2019338-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE Mitsubishi Chemical Corporation (JP) 2009-01-28 EP disclosed
US-20080193867-A1 Electrophotographic Photoreceptor and Image-Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2008-08-14 US disclosed
US-20080193867-A1 Electrophotographic Photoreceptor and Image-Forming Apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2008-08-14 US disclosed
EP-1837707-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE-FORMING APPARATUS Mitsubishi Chemical Corporation (JP) 2007-09-26 EP disclosed
EP-1813991-A1 COATING LIQUID FOR UNDERCOATING LAYER FORMATION, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR HAVING UNDERCOATING LAYER FORMED BY COATING OF SAID COATING LIQUID Mitsubishi Chemical Corporation (JP) 2007-08-01 EP disclosed
US-20070096089-A1 Organic semiconductor diode NITTO DENKO CORPORATION (JP) 2007-05-03 US disclosed
US-7211824-B2 Organic semiconductor diode NITTO DENKO CORPORATION (JP) 2007-05-01 US disclosed
US-20070020407-A1 Elliptically polarizing plate, liquid crystal panel, liquid crystal display device, and image display device NITTO DENKO CORPORATION (JP) 2007-01-25 US disclosed
US-7160485-B2 Lyotropic liquid crystal systems based on perylenetetracarboxylic acid dibenzimidazole sulfoderivatives, related anisotropic films, and methods for making NITTO DENKO CORPORATION (JP) 2007-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10815222-B2 Compounds for use in the treatment of kinetoplastid infection NISCH, TK2, FDPS ALDH1A1 1658/4885KMT2A 1062/4885HTT 3609/4885
US-20210220251-A1 HAIR COLORING COMPOSITION AND METHODS FOR ITS APPLICATION AND REMOVAL KRT18, TYR, CD99 ALDH1A1 487/4885KMT2A 831/4885HTT 2533/4885
US-20200095232-A1 COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION NISCH, TK2, FDPS ALDH1A1 1658/4885KMT2A 1062/4885HTT 3609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.