Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | THRB | P10828 | 5/20 | 0.61 |
| ▸ | RECQL | P46063 | 5/20 | 0.61 |
| ▸ | FGB | P02675 | 1/20 | 0.53 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 2/20 | 0.47 |
| ▸ | BRD1 | O95696 | 2/20 | 0.47 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.47 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979485 | 0.89 | THRB (0.50) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL19865855 | 0.83 | MAPT (0.44) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL17979432 | 0.80 | THRB (0.43) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL17979542 | 0.80 | MAPT (0.41) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL17979543 | 0.80 | MAPT (0.41) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL17979340 | 0.73 | BRPF1 (0.37) | ALDH1A1KMT2AMAPTBRPF1POLB | |
| SCHEMBL17979482 | 0.73 | BRPF1 (0.41) | ALDH1A1KMT2AMEN1MAPTBRPF1 | |
| SCHEMBL19865934 | 0.73 | MAPT (0.43) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL30379716 | 0.73 | KMT2A (0.58) | ALDH1A1KMT2AMEN1MAPTTHRB | |
| SCHEMBL26089763 | 0.73 | KMT2A (0.58) | ALDH1A1KMT2AMEN1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10392348-B2 | 2-oxo-3,4-dihydroquinoline compounds as plant growth regulators | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-27 | — | — | US | disclosed |
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |
| US-20180044297-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-02-15 | — | — | US | disclosed |
| EP-3256447-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128317-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10392348-B2 | 2-oxo-3,4-dihydroquinoline compounds as plant growth regulators | CDC25B, OSR1, CDC25C | ALDH1A1 2126/4885KMT2A 1473/4885MEN1 4792/4885 |
| US-20180044297-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | CDC25B, OSR1, CDC25C | ALDH1A1 2126/4885KMT2A 1473/4885MEN1 4792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.