Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | MEN1 | O00255 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 6/20 | 0.37 |
| ▸ | RECQL | P46063 | 5/20 | 0.37 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17979542 | 1.00 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ABRPF1 | |
| SCHEMBL19865855 | 0.83 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2ABRPF1 | |
| SCHEMBL17979460 | 0.80 | ALDH1A1 (0.61) | MAPTALDH1A1MEN1KMT2ABRPF1 | |
| SCHEMBL17979485 | 0.78 | THRB (0.50) | MAPTALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL17979432 | 0.75 | THRB (0.43) | MAPTALDH1A1MEN1KMT2ATHRB | |
| SCHEMBL17979340 | 0.73 | BRPF1 (0.37) | MAPTALDH1A1KMT2ABRPF1POLB | |
| SCHEMBL17979482 | 0.73 | BRPF1 (0.41) | MAPTALDH1A1MEN1KMT2ABRPF1 | |
| SCHEMBL19865934 | 0.73 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2ABRPF1 | |
| SCHEMBL17979397 | 0.69 | HDAC1 (0.43) | MAPTPOLBLMNATP53 | |
| SCHEMBL17979395 | 0.69 | HDAC1 (0.43) | MAPTPOLBLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3256447-B1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-06-05 | — | — | EP | disclosed |
| EP-3256447-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | Syngenta Participations AG (CH) | 2017-12-20 | — | — | EP | disclosed |
| WO-2016128317-A1 | 2-OXO-3,4-DIHYDROQUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-18 | — | — | WO | disclosed |