SCHEMBL1797974

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26023591	0.88	TRPV4 (0.43)	TRPV4KIF11ARMRGPRX4TRPA1
	SCHEMBL11236994	0.84	PDE3B (0.41)	PDE3BPDE3AARSLC6A2SLC6A4
	SCHEMBL1037550	0.81	TRPV4 (0.49)	TRPV4KIF11ARMRGPRX4EPHX2
	SCHEMBL22193269	0.81	TRPV4 (0.53)	TRPV4KIF11ARMRGPRX4EPHX2
	SCHEMBL24177142	0.79	TRPV4 (0.50)	TRPV4KIF11ARMRGPRX4EPHX2
	SCHEMBL19478936	0.79	TRPV4 (0.46)	TRPV4KIF11ARMRGPRX4
	SCHEMBL12884378	0.78	FFAR1 (0.42)	KIF11CYP19A1
	SCHEMBL2263818	0.78	TRPV4 (0.49)	TRPV4KIF11ARMRGPRX4EPHX2
	SCHEMBL24146520	0.78	RXRA (0.50)	TRPV4KIF11ARMRGPRX4EPHX2
	SCHEMBL10298852	0.78	TRPV4 (0.49)	TRPV4KIF11ARMRGPRX4EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.