Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 5/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26020663 | 0.87 | TRPV4 (0.40) | TRPV4KIF11SLC22A12NR3C1PGR | |
| SCHEMBL22193269 | 0.83 | TRPV4 (0.53) | TRPV4KIF11SLC22A12MRGPRX4AR | |
| SCHEMBL19478936 | 0.80 | TRPV4 (0.46) | TRPV4KIF11MRGPRX4AR | |
| SCHEMBL13315163 | 0.79 | NR3C1 (0.48) | TRPV4KIF11SLC22A12NR3C1PGR | |
| SCHEMBL2263818 | 0.79 | TRPV4 (0.49) | TRPV4KIF11SLC22A12MRGPRX4AR | |
| SCHEMBL10298852 | 0.79 | TRPV4 (0.49) | TRPV4KIF11SLC22A12MRGPRX4AR | |
| SCHEMBL24146520 | 0.79 | RXRA (0.50) | TRPV4KIF11SLC22A12MRGPRX4AR | |
| SCHEMBL1037550 | 0.79 | TRPV4 (0.49) | TRPV4KIF11SLC22A12MRGPRX4AR | |
| SCHEMBL26020302 | 0.79 | TRPV4 (0.45) | TRPV4KIF11MRGPRX4ARSLC6A2 | |
| SCHEMBL1797974 | 0.79 | TRPV4 (0.45) | TRPV4KIF11MRGPRX4AREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
| WO-2022001767-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | 武汉朗来科技发展有限公司 | 2022-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TRPC5, TRPC1, GOT1 | TRPV4 77/4885KIF11 1668/4885SLC22A12 672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.