Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 8/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1797974 | 0.88 | TRPV4 (0.45) | TRPV4KIF11TRPA1ARMRGPRX4 | |
| SCHEMBL22193269 | 0.79 | TRPV4 (0.53) | TRPV4KIF11ARMRGPRX4EPHX2 | |
| SCHEMBL1037550 | 0.79 | TRPV4 (0.49) | TRPV4KIF11ARMRGPRX4EPHX2 | |
| SCHEMBL24177142 | 0.76 | TRPV4 (0.50) | TRPV4KIF11ARMRGPRX4EPHX2 | |
| SCHEMBL19478936 | 0.76 | TRPV4 (0.46) | TRPV4KIF11ARMRGPRX4 | |
| SCHEMBL10298852 | 0.76 | TRPV4 (0.49) | TRPV4KIF11ARMRGPRX4EPHX2 | |
| SCHEMBL2263818 | 0.76 | TRPV4 (0.49) | TRPV4KIF11ARMRGPRX4EPHX2 | |
| SCHEMBL24146520 | 0.76 | RXRA (0.50) | TRPV4KIF11ARMRGPRX4EPHX2 | |
| SCHEMBL26020302 | 0.75 | TRPV4 (0.45) | TRPV4KIF11ARMRGPRX4 | |
| SCHEMBL27929091 | 0.73 | TRPV4 (0.46) | TRPV4KIF11TRPA1ARMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257382-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | TRPC5, TRPC1, GOT1 | TRPV4 77/4885KIF11 1668/4885TRPA1 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.