Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 14/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986280 | 0.89 | TSHR (0.42) | PKMRAB9AKDM4EALDH1A1MAPT | |
| Aspirin SCHEMBL4160555 | 0.83 | PTGS2 (0.53) | TMEM97MRGPRX4SMN1; SMN2PKMRAB9A | |
| Aspirin SCHEMBL4160561 | 0.83 | PTGS2 (0.53) | TMEM97MRGPRX4SMN1; SMN2PKMRAB9A | |
| SCHEMBL220610 | 0.81 | TMEM97 (0.57) | TMEM97MRGPRX4SMN1; SMN2PKMRAB9A | |
| Benzene SCHEMBL16599421 | 0.78 | KDM4E (0.51) | PKMKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL6400514 | 0.77 | KDM4E (0.52) | RAB9AKDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16599401 | 0.76 | PTGS2 (0.45) | SMN1; SMN2RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL12861015 | 0.75 | MAOB (0.58) | TMEM97MRGPRX4ALDH1A1 | |
| SCHEMBL6401897 | 0.74 | CFD (0.65) | MRGPRX4RAB9AKDM4EUSP2ALDH1A1 | |
| SCHEMBL4160557 | 0.73 | PTGS2 (0.55) | TMEM97MRGPRX4SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10793509-B2 | Compounds useful in the treatment of neoplastic diseases | UNIVERSITÄT ZU KOLN (DE) | 2020-10-06 | — | — | US | disclosed |
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2016-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160237023-A1 | COMPOUNDS USEFUL IN THE TREATMENT OF NEOPLASTIC DISEASES | APC, BRCA1, VHL | TMEM97 3528/4885MRGPRX4 2750/4885SMN1; SMN2 346/4885 |
| US-10793509-B2 | Compounds useful in the treatment of neoplastic diseases | APC, BRCA1, VHL | TMEM97 3528/4885MRGPRX4 2750/4885SMN1; SMN2 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.